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Vonoprazan in Management of Refractory Gastroesophageal Reflux Disease: An Indian Expert Group Consensus Statements.
J Assoc Physicians India
March 2025
Assistant Professor, Department of Gastroenterology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Background: Approximately, 40% of gastroesophageal reflux disease (GERD) patients experience insufficient symptom relief from proton-pump inhibitors (PPI), resulting in PPI-refractory GERD (rGERD).
Objective: To review the existing literature and develop an Indian expert group consensus statement on the place of vonoprazan in the management of rGERD.
Materials And Methods: A panel of 35 leading Indian gastroenterologists extensively reviewed the literature to develop consensus statements for the management of rGERD in Indian patients, with a focus on the newly available potassium-competitive acid blocker (P-CAB), vonoprazan.
Endoscopic transorbital approach for the management of spheno-orbital meningiomas: A systematic review and meta-analysis.
Neurochirurgie
March 2025
Neurosurgical Oncology Division - Barretos Cancer Hospital, Barretos, SP, Brazil.
Introduction: Meningioma is the most common benign tumor in the central nervous system and may arise from the sphenoid wing region. The tumor can involve the cavernous sinus medially, periorbital and orbital apex structures anteriorly, and infratemporal fossa inferiorly. Surgical approaches more currently used include the fronto-temporal approach, the pterional approach, and even the frontotemporal-orbitozygomatic approach.
View Article and Find Full Text PDFAhmedabad declaration: A framework to combat growing epidemic of young-onset type 2 diabetes in Asia.
Diabetes Metab Syndr
February 2025
Madras Diabetes Research Foundation [ICMR- Collaborating Centre of Excellence (ICMR-CCoE)], India; Dr. Mohan's Diabetes Specialties Centre (IDF Centre of Excellence in Diabetes Care), Chennai, India.
Aim: Rising prevalence of Type 2 Diabetes (T2D) among young Asians has emerged as a public health crisis that threatens the long-term health, economic stability, and productivity of nations across Asia (1). Early-onset T2D poses unique challenges, including higher rates of undiagnosed cases, more aggressive disease progression, an increased risk of chronic complications and higher mortality (2). Hyperglycemia during the reproductive age especially among the female population can potentially have transgenerational impact through epigenetic changes.
View Article and Find Full Text PDFThree-dimensional (3D) ultrasound imaging for quantitative assessment of frontal cobb angles in patients with idiopathic scoliosis - a systematic review and meta-analysis.
BMC Musculoskelet Disord
March 2025
SH Ho Scoliosis Research Lab, Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University, Hong Kong, Hong Kong.
Background: Measurement of Cobb angle in the frontal plane from radiographs is the gold standard of quantifying spinal deformity in adolescent idiopathic scoliosis (AIS). As a radiation free alternative, ultrasonography (USG) for quantitative measurement of frontal cobb angles has been reported. However, a systematic review and meta-analysis on the reliability of ultrasound comparing with the gold standard have not yet been reported.
View Article and Find Full Text PDFNeuroendoscopy Training.
Asian J Neurosurg
March 2025
Department of Neurosciences, Apex Hospital and Research Centre, Jabalpur, Madhya Pradesh, India.
Neuroendoscopy can be learnt by assisting or doing live human surgery, cadaver dissection with or without augmented pulsatile vessel and cerebrospinal fluid (CSF) perfusion, and practicing on live animal, dead animal model, synthetic models, three-dimensional printing model with or without augmentation with animal, cadaver tissue, pulsatile vessel and reconstructed CSF model, virtual reality (VR) simulator, and hybrid simulators (combined physical model and VR model). Neurosurgery skill laboratory with basic and advanced learning should be there in all teaching hospitals. Skills can be transferred from simulation model or VR to cadaver to live surgery.
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