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Approaches to Incorporation of Preferences into Health Economic Models of Genomic Medicine: A Critical Interpretive Synthesis and Conceptual Framework.
Appl Health Econ Health Policy
January 2025
Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Introduction: Genomic medicine has features that make it preference sensitive and amenable to model-based health economic evaluation. Preferences of patients, caregivers, and clinicians related to the uptake and delivery of genomic medicine technologies and services that are not captured in health state utility weights can affect the intervention's cost-effectiveness and budget impact. However, there is currently no established or agreed-on approach for integrating preference information into economic evaluations.
View Article and Find Full Text PDFRapid Increase in Soil Respiration and Reduction in Soil Nitrate Availability Following CO Enrichment in a Mature Oak Forest.
ACS Omega
January 2025
Birmingham Institute of Forest Research (BIFoR), University of Birmingham, Edgbaston B15 2TT, U.K.
In the future, with elevated atmospheric CO (eCO), forests are expected to increase woody biomass to capture more carbon (C), though this is dependent on soil nutrient availability. While young forests may access unused nutrients by growing into an unexplored soil environment, it is unclear how or if mature forests can adapt belowground under eCO. Soil respiration ( ) and nutrient bioavailability are integrative ecosystem measures of below-ground dynamics.
View Article and Find Full Text PDFUnveiling the role of saltmarshes as coastal potassium sinks: A perspective from porewater-derived potassium exchange.
Sci Total Environ
January 2025
Key Laboratory of Coastal Environment and Resources of Zhejiang Province, School of Engineering, Westlake University, Hangzhou 310024, China. Electronic address:
Saltmarshes serve as repositories for various metal species, primarily due to vegetation removal and mineralization processes. However, the significance of potassium (K), one of the three major nutrients (nitrogen, phosphorus, and K) essential for plant growth, has often been overlooked, particularly in the context of saltmarshes where the mechanisms of K transport via porewater exchange remain poorly understood. To address this knowledge gap, we conducted field observations and laboratory analysis, and developed a Rn mass balance model to quantify K fluxes via porewater exchange under physical, biological, and anthropogenic drivers.
View Article and Find Full Text PDFCost-effectiveness and budget impact analysis of peritoneal dialysis and haemodialysis in South Africa.
BMC Health Serv Res
January 2025
SAMRC/Wits Centre for Health Economics and Decision Science - PRICELESS SA, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 2193, South Africa.
Background: More than 800 million people are affected by chronic kidney disease (CKD) worldwide. In South Africa, the prevalence of CKD increased by 67% between 1999 and 2006. Haemodialysis (HD), peritoneal dialysis (PD), and kidney transplant are the three main modalities used for managing end stage kidney disease.
View Article and Find Full Text PDFState laws on intimate partner violence witnessed by children in the United States.
J Public Health Policy
January 2025
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Intimate partner violence (IPV) is common, and almost half of all IPV takes place in relationships with children in the home. We inventoried laws in the 50 states and the District of Columbia in the United States of America (USA) focused on addressing IPV committed in the presence of children, as these laws could help prevent or remediate this critical health and social issue. Using WestLaw, a web-based legal research service, we identified over 1,200 statutes and 500 regulations.
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