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| http://dx.doi.org/10.11604/pamj.2016.23.14.8270 | DOI Listing |
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Transorbital laser surgery for epilepsy: Anatomic-radiological feasibility of transorbital magnetic resonance imaging-guided laser interstitial thermal therapy (MRIgLITT) for amygdalohippocampectomy in refractory epilepsy.
Clin Neurol Neurosurg
January 2025
Department of Neurosurgery, Hospital Clínic de Barcelona, Barcelona, Spain; Universitat de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Objective: to study the anatomical feasibility of laser fiber insertion for interstitial thermal therapy via transorbital approach to the temporo-mesial structures (amygdala-hippocampus-parahippocampus complex).
Methods: Anatomical dissections were performed bilaterally on two human cadaveric heads via a transorbital approach, in which screws and laser fibers were used for magnetic resonance imaging-guided laser interstitial thermal therapy (MRIgLITT) assisted by neuronavigation. In addition, eight transorbital trajectories were simulated using the transorbital entry points obtained from a cadaveric radiological study of four patients previously operated on for mesial temporal lobe epilepsy.
David Ferrier's second monkey ('monkey F'): The inaugural experimental studies of the auditory cortex.
J Hist Neurosci
January 2025
Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
The story of David Ferrier's demonstration at the International Medical Congress in London in August 1881 of a monkey experimentally rendered hemiplegic by a focal surgical brain lesion-prompting Charcot's observation, "C'est un malade!"-is well known as a seminal event in the history of the localization of functions in the cerebral cortex. Less well known is the fact that, on the same occasion, Ferrier demonstrated a second monkey, known as monkey F, apparently deaf as a consequence of bilateral temporo-sphenoidal brain lesions. The purpose of this article is, first, to give a chronological account of this demonstration and subsequent related events, including Ferrier's trial under the Vivisection Act, the publication of the pathological findings in the animal's brain, the dispute about the localization of the "auditory centre" with Edward Schäfer, and the first glimmerings of human homologues of cortical deafness.
View Article and Find Full Text PDFCatastrophic antiphospholipid syndrome of pregnancy with acute massive cerebral infarction: A case report.
Medicine (Baltimore)
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Department of Oncology, Loudi Central Hospital, Loudi, China.
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Patient Concerns: A 21-year-old patient was 32 weeks and 5 days pregnant when she presented to the hospital with a 7-hour history of sudden onset of left-sided limb weakness with no apparent cause.
Family lexicon: Using language models to encode memories of personally familiar and famous people and places in the brain.
PLoS One
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Max Planck Institute for Human Cognitive and Brain Sciences, Cognition and Plasticity Research Group, Leipzig, Germany.
Knowledge about personally familiar people and places is extremely rich and varied, involving pieces of semantic information connected in unpredictable ways through past autobiographical memories. In this work, we investigate whether we can capture brain processing of personally familiar people and places using subject-specific memories, after transforming them into vectorial semantic representations using language models. First, we asked participants to provide us with the names of the closest people and places in their lives.
View Article and Find Full Text PDFCladosporium cladosporioides brain abscess: an enigmatic case.
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Department of Microbiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
A fifteen-year-old boy was brought to emergency department with complaints of altered sensorium, aphasia and right sided hemiparesis following severe dengue one month back. On physical examination, tone was flaccid and power was diminished in right upper and lower limbs. Reflexes were diminished in all four limbs.
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