AI Article Synopsis
- Some people with chronic hepatitis C also have autoimmune problems, which means their immune system attacks their own body.
- It used to be hard to treat these patients because the treatments could make their autoimmune issues worse or not work well against the virus.
- This report shows that 3 patients got better quickly with new antiviral treatments, suggesting the virus might be causing some of their autoimmune issues.
Article Abstract
Autoimmune phenomena are common in patients with chronic hepatitis C. Management of chronic hepatitis C/autoimmune hepatitis syndrome has until recently been problematic due to the adverse effects of interferon on autoimmune processes and immunosuppression on viral replication. In this report we describe 3 patients with chronic hepatitis C/autoimmune hepatitis overlap syndrome who responded rapidly to direct acting anti-viral therapy. The resolution of the autoimmune process supports a direct viral role in its pathophysiology.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867421 | PMC |
| http://dx.doi.org/10.4254/wjh.v8.i14.632 | DOI Listing |
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