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Longitudinal Associations of Experiential and Reflective Dimensions of Meaning in Life With Psychopathological Symptoms.
Clin Psychol Eur
September 2024
Department of Psychology, Institute for Mental Health and Behavioral Medicine, HMU Health and Medical University Potsdam, Potsdam, Germany.
Background: Rather than being rooted in deliberate reflection, the experience of meaning has been shown to evolve from intuitive processes (Heintzelman & King, 2013b, https://doi.org/10.1007/978-94-007-6527-6_7).
View Article and Find Full Text PDFDifferential Lipid Signatures of Lumbar and Cisternal Cerebrospinal Fluid.
Biomolecules
November 2024
Department of Neuroscience, University of Copenhagen, 2200 Copenhagen, Denmark.
Background: The molecular composition of cerebrospinal fluid (CSF) is often used as a key indicator of biochemical alterations within distinct brain and spinal cord fluid compartments. The CSF protein content in lumbar CSF samples is widely employed as a biomarker matrix for diagnosing brain-related pathological conditions. CSF lipid profiles may serve as promising complementary diagnostics, but it remains unresolved if the lipid distribution is consistent along the neuroaxis.
View Article and Find Full Text PDFEvolution of dosimetric parameters through PRRT and potential impact on clinical practice: data from the prospective phase II LUMEN study.
EJNMMI Res
November 2024
Nuclear Medicine Department, ENETS Centre of Excellence, Institut Jules Bordet, Université Libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (H.U.B), Brussels, Belgium.
Background: Peptide receptor radionuclide therapy (PRRT) with [Lu]Lu-DOTA-TATE has emerged as a promising treatment for gastroenteropancreatic neuroendocrine tumours (GEP-NETs). Its treatment protocol is currently standardised for all patients, resulting in different patient outcomes. This study investigates the variability of tumours and organs-at-risk (kidneys and red marrow) dosimetric parameters across treatment cycles in patients with pancreatic and intestinal NETs.
View Article and Find Full Text PDFHES1 revitalizes the functionality of aged adipose-derived stem cells by inhibiting the transcription of STAT1.
Stem Cell Res Ther
November 2024
Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, China.
Background: The effectiveness of adipose-derived stem cells (ADSCs) in therapy diminishes with age. It has been reported that transcription factors (TFs) play a crucial role in the aging and functionality of stem cells. Nevertheless, there is limited understanding regarding the involvement of TFs in the aging mechanism of ADSCs.
View Article and Find Full Text PDFA graphite thermal Tesla valve driven by hydrodynamic phonon transport.
Nature
October 2024
Institute of Industrial Science, The University of Tokyo, Tokyo, Japan.
Article Synopsis
- The Tesla valve aids in controlling fluid flow in tiny systems, inspiring designs for modern electronic and thermal devices using fluid-like principles.
- Unlike fluid systems, thermal rectification of phonons (energy carriers in solids) is more complex due to fewer interactions and less liquid-like behavior.
- Recent studies on phonon behavior in graphite led to a micrometer-scale Tesla valve, achieving a 15.2% difference in heat conduction at low temperatures, pushing forward thermal management in small electronic devices.
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