AI Article Synopsis
- The study investigates the link between brachial-ankle pulse wave velocity and intracranial arterial stenosis in 834 stroke-free hypertensive patients, highlighting its relevance among Asians.
- Results indicated that higher brachial-ankle pulse wave velocity (top decile) was significantly associated with an increased risk of intracranial arterial stenosis, especially in individuals under 65 years old.
- The findings suggest that measuring brachial-ankle pulse wave velocity could serve as a simple method to identify hypertensive patients at higher risk for intracranial arterial stenosis, aiding in early detection.
Article Abstract
Background: Intracranial arterial stenosis is a common cause of ischemic stroke in Asians. We therefore sought to explore the relationship of brachial-ankle pulse wave velocity and intracranial arterial stenosis in 834 stroke-free hypertensive patients.
Methods: Intracranial arterial stenosis was evaluated through computerized tomographic angiography. Brachial-ankle pulse wave velocity was measured by an automated cuff device.
Results: The top decile of brachial-ankle pulse wave velocity was significantly associated with intracranial arterial stenosis (P = .027, odds ratio = 1.82; 95% confidence interval: 1.07-3.10). The patients with the top decile of brachial-ankle pulse wave velocity showed 56% higher risk for the presence of intracranial arterial stenosis to the whole population, which was more significant in patients younger than 65 years old. We also found that brachial-ankle pulse wave velocity related to both intracranial arterial stenosis and homocysteine.
Conclusion: Our study showed the association of brachial-ankle pulse wave velocity with asymptomatic intracranial arterial stenosis in hypertension patients, especially in relative younger subjects. Brachial-ankle pulse wave velocity might be a relatively simple and repeatable measurement to detect hypertension patients in high risk of intracranial arterial stenosis.
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| http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.04.008 | DOI Listing |
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