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Interrater reliability and agreement of the NEUMOBACT checklist about infection-prevention performance of intensive care nurses in simulation-based scenarios.
PLoS One
December 2024
Department of Fundamental and Clinical Care Nursing, Hospitalet del Llobregat, Universitat de Barcelona, Campus de Bellvitge, Barcelona, Spain.
Objective: To analyse the interrater reliability of the NEUMOBACT checklist and verify whether consistent results are reproducible.
Methods: A validation study with a cross-sectional design, compliant with the GRRAS checklist, among ICU nurses attending a SIMULAZERO course with an Objective Structured Clinical Evaluation simulation format, to verify transfer from theory to clinical practice of knowledge and skills in ventilator-associated pneumonia (VAP) and catheter-related bacteraemia (CRB) prevention. A minimum sample size of 111 pairs of nurse raters was calculated.
Mortality predictors and definition proposal for complicated coagulase-negative Staphylococcus bacteremia. A multicenter prospective cohort study.
Clin Microbiol Infect
December 2024
Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario Virgen Macarena, Seville, Spain; Departamentos de Medicina y Microbiología, Facultad de Medicina, Universidad de Sevilla, Seville, Spain; Instituto de Biomedicina de Sevilla (IBiS)/CSIC, 41009, Seville, Spain; CIBERINFEC, Instituto de Salud Carlos III, 28029, Madrid, Spain. Electronic address:
Objective: To explore a definition for complicated coagulase-negative staphylococci bloodstream infections (CoNS BSI), and to identify predictors for mortality.
Methods: Prospective cohort study conducted from October 2016 to March 2017 in 26 Spanish hospitals. Complicated CoNS BSI criteria included lack of early catheter removal in catheter-related cases, foreign indwelling implant, persistent bacteremia, fever ≥72 hours on active therapy, metastatic infection or deep-seated focus and infective endocarditis.
Subsequent bacteremia associated with intravascular catheter colonization with Staphylococcus aureus, Gram-negative rods, and Candida species in children.
J Infect Chemother
December 2024
Center for Postgraduate Education and Training, National Center for Child Health and Development, Tokyo, Japan.
Subsequent bacteremia developed in 14% of patients with positive catheter tip cultures but concurrent negative blood cultures. The occurrence of subsequent bacteremia did not differ significantly by pathogens (Staphylococcus aureus, Gram-negative rods [GNR], and Candida spp.).
View Article and Find Full Text PDFImpact of a nurse practitioner-led dedicated outpatient parenteral antibiotic therapy clinic on patient outcomes and administrative workload: a retrospective cohort study.
Ther Adv Infect Dis
December 2024
Division of Infectious Diseases, University of Toledo College of Medicine and Life Sciences, 3000 Arlington Avenue, Mail Stop 1186, Toledo, OH 43614, USA.
Background: Outpatient parenteral antibiotic therapy (OPAT) enhances patient safety, improves outcomes, and reduces healthcare costs by decreasing 30-day readmissions and adverse events. However, the optimal structure and follow-up protocols for OPAT programs remain undefined. Identifying high-risk patients for readmission and managing adverse drug events (ADEs) are critical components of OPAT care.
View Article and Find Full Text PDFPathogenic Burden, Antimicrobial Resistance Pattern and Clinical Outcome of Nosocomial Bloodstream Infections in Intensive Care Unit.
J Intensive Care Med
December 2024
Department of Critical Care and Anaesthesiology, All India Institute of Medical Sciences, Jodhpur, India.
Nosocomial bloodstream infections with multidrug-resistant microorganisms have become a common health threat in intensive care settings worldwide. Understanding antimicrobial resistance and the outcomes of these infections is crucial for addressing this issue. This study aimed to investigate the burden, antimicrobial resistance, and 28-day outcomes of nosocomial bloodstream infections in the intensive care unit.
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