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http://dx.doi.org/10.1097/CCM.0000000000001588 | DOI Listing |
J Trauma Acute Care Surg
March 2025
From the Division of Trauma and Burn Surgery (M.S.K., G.J.S., T.M.S., A.H.M., R.S.B.), Children's National Hospital, Washington, DC; Division of Pediatric Surgery (N.J.A., A.M.G., A.R.J.), University of California San Francisco Benioff Children's Hospitals, San Francisco; Department of Surgery (N.J.A., A.M.G.), University of California, San Francisco, East Bay, Oakland, California; Division of Emergency Medicine (S.J.R., J.C.L.) and Division of Pediatric Surgery (K.L.G.), Nationwide Children's Hospital; Ohio State University College of Medicine (K.L.G., J.C.L.), Columbus, Ohio; and Department of Surgery (A.R.J.), University of California San Francisco, San Francisco, California.
Background: Bleeding is the leading cause of preventable death in trauma. Early identification of hemorrhage improves patient outcomes. Current triage tools for predicting hemorrhage rely on transfusion receipt as a surrogate outcome, indicating that blood was needed.
View Article and Find Full Text PDFAntimicrob Steward Healthc Epidemiol
February 2025
Medical Microbiology and Infectious Diseases, Infection Prevention and Control Unit, Jewish General Hospital, Montreal, QC, Canada.
Objective: To develop and validate an automated surveillance system for healthcare-associated infections (HA-CDI).
Design: Multicenter cohort study.
Setting: 16 acute care hospitals.
Nat Rev Cancer
February 2025
Appendix Cancer Pseudomyxoma Peritonei (ACPMP) Research Foundation, Springfield, PA, USA.
Tumours of the appendix - a vestigial digestive organ attached to the colon - are rare. Although we estimate that around 3,000 new appendiceal cancer cases are diagnosed annually in the USA, the challenges of accurately diagnosing and identifying this tumour type suggest that this number may underestimate true population incidence. In the current absence of disease-specific screening and diagnostic imaging modalities, or well-established risk factors, the incidental discovery of appendix tumours is often prompted by acute presentations mimicking appendicitis or when the tumour has already spread into the abdominal cavity - wherein the potential misclassification of appendiceal tumours as malignancies of the colon and ovaries also increases.
View Article and Find Full Text PDFCureus
January 2025
School of Public Health, Kerala University of Health Sciences, Trivandrum, IND.
Introduction Fever is a common manifestation of acute illness among children, and it is essential to measure body temperature accurately in pediatric clinical practice. Various methods are in use, but no gold standard exists for body temperature measurement among this population. Latent class analysis (LCA) is increasingly used to assess diagnostic accuracy in the absence of a gold standard.
View Article and Find Full Text PDFAcad Emerg Med
February 2025
Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Objective: Calibration and discrimination indicators alone are insufficient for evaluating the clinical usefulness of prediction models, as they do not account for the cost of misclassification errors. This study aimed to modify the Geriatric Trauma Outcome Score (GTOS) and assess the clinical utility of the modified model using net benefit (NB) and decision curve analysis (DCA) for predicting in-hospital mortality.
Methods: The Trauma Quality Improvement Program (TQIP) 2017 was used to identify geriatric trauma patients (≥ 65 years) treated at Level I trauma centers.
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