Sleepless in CKD: a novel risk factor for CKD progression?

Disorders of sleep have been associated with adverse outcomes in both the general population and in patients with chronic kidney disease. McMullan et al. add to this literature by demonstrating an association between short sleep duration and more rapid decline in glomerular filtration rate. We discuss the potential implications of these results but also offer some caution in over-interpretation of the data, given limitations in both the assessment of sleep as well as the kidney outcomes.