This position statement from the European Menopause and Andropause Society (EMAS) provides a care pathway for the maintenance of women's health during and after the menopause. It is designed for use by all those involved in women's health. It covers assessment, screening for diseases in later life, treatment and follow-up. Strategies need to be optimised to maintain postreproductive health, in part because of increased longevity. They encompass optimising diet and lifestyle, menopausal hormone therapy and non-estrogen-based treatment options for climacteric symptoms and skeletal conservation, personalised to individual needs.
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| http://dx.doi.org/10.1016/j.maturitas.2016.04.013 | DOI Listing |
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Aging women in Russia: Between sexless and sexy oldies.
J Women Aging
January 2025
Department of Sociology, European University at St. Petersburg, St Petersburg, Russia.
Women's sexuality as a dimension of embodied identity is shaped and constrained by social norms of gender and age and negotiated by women in complex ways. Discourses of hegemonic bodily normativity ascribe a sexless subjectivity to Russian women in their post-reproductive years, contributing to their social exclusion. At the same time, in modern Russian society a neoliberal concept of "successful active aging" is gradually changing understandings of aging, making later-life sexuality more visible and legitimate.
View Article and Find Full Text PDFAmyloid-β and phosphorylated tau screening in bottlenose dolphin (Tursiops truncatus) and striped dolphin (Stenella coeruleoalba) brains from Italy reveals distinct immunohistochemical patterns correlating with age and co-morbidity.
PLoS One
November 2024
Department of Comparative Biomedicine and Food Science, University of Padova, Legnaro (Padova), Italy.
Cetacean brains are uniquely adapted to diving, but can be affected by diseases and exposure to toxins, triggering neurodegenerative processes that may cause stranding. Some species exhibit a significant post-reproductive lifespan (PRLS), increasing the likelihood of observing cumulative and age-related pathology. Immunohistochemistry against amyloid-β and hyperphosphorylated tau proteins is increasingly implemented to assess Alzheimer's Disease-like neuropathology in cetaceans, but comparisons between geographically distinct populations, animals of different age groups, sex, and with concomitant pathologies are lacking.
View Article and Find Full Text PDFParity and post-reproductive mortality among U.S. Black and White women: Evidence from the health and retirement study.
PLoS One
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Department of Sociology, Aging Studies Institute and Center for Aging and Policy Studies, Maxwell School of Citizenship & Public Affairs, Syracuse University, Syracuse, NY, United States of America.
Population health research finds women's mortality risk associated with childlessness, low parity (one child), and high parity (6+ children) in a U-shaped pattern, although U.S. studies are inconsistent overall and by race/ethnicity.
View Article and Find Full Text PDFEndocrine Dyscrasia in the Etiology and Therapy of Alzheimer's Disease.
J Alzheimers Dis
September 2024
Geriatric Research, Education and Clinical Center, Veterans Administration Hospital and Department of Medicine, University of Wisconsin, Madison, WI, USA.
The increase in the incidence of dementia over the last century correlates strongly with the increases in post-reproductive lifespan during this time. As post-reproductive lifespan continues to increase it is likely that the incidence of dementia will also increase unless therapies are developed to prevent, slow or cure dementia. A growing body of evidence implicates age-related endocrine dyscrasia and the length of time that the brain is subjected to this endocrine dyscrasia, as a key causal event leading to the cognitive decline associated with aging and Alzheimer's disease (AD), the major form of dementia in our society.
View Article and Find Full Text PDFWestern diet-induced cognitive and metabolic dysfunctions in aged mice are prevented by rosmarinic acid in a sex-dependent fashion.
Clin Nutr
October 2024
Center for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy. Electronic address:
Background & Aims: Unhealthy lifestyles, such as chronic consumption of a Western Diet (WD), have been associated with increased systemic inflammation and oxidative stress (OS), a condition that may favour cognitive dysfunctions during aging. Polyphenols, such as rosmarinic acid (RA) may buffer low-grade inflammation and OS, characterizing the aging brain that is sustained by WD, promoting healthspan. The aim of this study was to evaluate the ability of RA to prevent cognitive decline in a mouse model of WD-driven unhealthy aging and to gain knowledge on the specific molecular pathways modulated within the brain.
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