The cumulative effect of bisphosphonates and statins on stress fractures. Is it a failure of steroid biosynthesis? Case Report.

Osteoporosis related fractures pose a significant economic and healthcare problem. There is a growing concern about increased numbers of stress or low energy fractures after bisphosphonates therapy. A 65-year-old woman is presented with a stress fracture of the left femur. From our point of view, this fracture was associated with a long-term statin and bisphosphonate therapy. We did not find a similar presentation in medical literature.