Background: Minimizing gap formation and maximizing the strength of patellar tendon repairs are 2 critical factors for successful healing of these injuries.
Purpose/hypothesis: The purpose of this study was to compare transosseous and screw-in anchor repair techniques to determine if there is a difference in gap formation and load to failure of the 2 constructs. The research hypotheses were that the anchor construct would have significantly less gap formation and would also have significantly greater load-to-failure strength.
Study Design: Controlled laboratory study.
Methods: A total of 24 porcine specimens were randomly assigned into transosseous and 4.75-mm polyetheretherketone (PEEK) screw-in anchor repair groups. The repairs were then completed using 2 No. 2 FiberWire sutures, and each specimen was cyclically loaded on a tensile test machine to 250 N for a total of 1000 cycles. Gap formation was measured at 1, 10, 250, 500, and 1000 cycles. Each specimen was loaded to failure after 1000 cycles. Independent t tests were conducted.
Results: Statistically significant gap formation and load-to-failure differences were found between the 2 repair techniques. The mean gap in the anchor group (2.16 ± 1.81 mm) was significantly less than that seen in the transosseous group (5.71 ± 1.58 mm) (P < .001). The mean load to failure of the anchor group (669.9 ± 91.8 N) was significantly higher than that of the transosseous group (582.8 ± 92.6 N) (P = .03).
Conclusion: The results support the 2 study hypotheses. These findings suggest that the 4.75-mm PEEK screw-in anchor construct may be superior to the transosseous technique for minimizing gap formation and improving load-to-failure strength after surgical repair of the patellar tendon.
Clinical Relevance: The use of the suture anchor technique in patellar tendon repair may support early load-bearing rehabilitation.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1177/0363546516643811 | DOI Listing |
During type 1 diabetes (T1D) progression, beta cells become dysfunctional and exhibit reduced first-phase insulin release. While this period of beta cell dysfunction is well established, its cause and underlying mechanism remain unknown. To address this knowledge gap, live human pancreas tissue slices were prepared from autoantibody- negative organ donors without diabetes (ND), donors positive for one or more islet autoantibodies (AAb+), and donors with T1D within 0-4 years of diagnosis (T1D+).
View Article and Find Full Text PDFUnlabelled: Although tryptophan (Trp) is the largest and most structurally complex amino acid, it is the least abundant in the proteome. Its distinct indole ring and high carbon content enable it to generate various biologically active metabolites such as serotonin, kynurenine (Kyn), and indole-3-pyruvate (I3P). Dysregulation of Trp metabolism has been implicated in diseases ranging from depression to cancer.
View Article and Find Full Text PDFNanoscale
January 2025
Department of Physics, Indian Institute of Technology Patna, Bihta, Bihar, 801106, India.
In this study, we investigate a novel hybrid borocarbonitride (bpn-BCN) 2D material inspired by recent advances in carbon biphenylene synthesis, using first-principles calculations and semi-classical Boltzmann transport theory. Our analysis confirms the structural stability of bpn-BCN through formation energy, elastic coefficients, phonon dispersion, and molecular dynamics simulations at 300 K and 800 K. The material exhibits an indirect band gap of 0.
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
Guangdong Basic Research Center of Excellence for Ecological Security and Green Development, Guangdong University of Technology, Guangzhou 510006, China.
The massive production and widespread use of plastics have resulted in a growing marine plastic pollution problem. Cold seep ecosystems are maintained by microorganisms related to nitrogen and carbon cycling that occur in deep-sea areas, where cold hydrocarbon-rich water seeps from the ocean floor. Little is known about plastic pollution in this ecosystem.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Department of Semiconductor Engineering, Gyeongsang National University, Jinjudae-ro 501beon-gil, Jinju-si, Gyeongsangnam-do, Republic of Korea.
Organic photodetectors (OPDs) are cheaper and more flexible than conventional photodetectors based on inorganic precursors, but their wider commercial application is limited by their low electron extraction efficiency under reverse bias conditions (when operating under photoconductive mode). Zinc oxide (ZnO) has shown promise as an electron transport layer for OPDs owing to its wide band gap, but its electron extraction efficiency has been limited by issues such as photoinstability and the formation of surface detects. This study investigated the effects of doping ZnO nanoparticles with indium gallium (i.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!