Neisseria gonorrhoeae is one of the most prevalent sexually transmitted pathogen with the vast majority of reported cases diagnosed at urogenital sites. While urethral gonococcal infections in men usually present with penile discharge and dysuria, pharynx and rectal infections are often asymptomatic. The Centers for Disease Control and Prevention recommend that sexually active men who have sex with men (MSM) be screened at least annually for urethral, pharyngeal and rectal gonorrhea, considering sexual exposure history, and every 3 to 6 months if higher-risk behaviours are reported. However, despite CDC's guidelines screening recommendations, low rates of testing among MSM are reported, such as urethral-only screening which may entail missing pharyngeal and rectal gonococcal infection. We present a case report of gonorrhea with multiple anatomic sites infection in a young MSM. Inspite of clinical presentation involving urogenital symptoms only, a sexual history based valutation allowed to detect asymptomatic pharyngeal and rectal infections.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Doxycycline Postexposure Prophylaxis and Bacterial Sexually Transmitted Infections Among Individuals Using HIV Preexposure Prophylaxis.
JAMA Intern Med
January 2025
Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
Importance: Doxycycline postexposure prophylaxis (doxyPEP) has been shown to decrease the incidence of bacterial sexually transmitted infections (STIs) among people assigned male sex at birth in clinical trials, but data from clinical practice are limited.
Objective: To describe early uptake of doxyPEP and evaluate changes in STI incidence following doxyPEP initiation.
Design, Setting, And Participants: This retrospective cohort study of adults (aged ≥18 years) dispensed HIV preexposure prophylaxis (PrEP) at Kaiser Permanente Northern California during November 1, 2022, to December 31, 2023, examined electronic health record data to compare HIV PrEP users dispensed and not dispensed doxyPEP and rates of bacterial STIs before and after starting doxyPEP.
Screening sites for detection of carbapenemase-producers- a retrospective cohort study.
Antimicrob Resist Infect Control
December 2024
Division of Infectious Diseases and Infection Control, Hospital Epidemiology, University Hospital Basel, University Basel, Petersgraben 4, CH-4031, Basel, Switzerland.
While screening the rectal site and urine may be appropriate for detection of carbapenemase-producing Enterobacterales, respiratory samples, throat and wound swabs may increase the sensitivity of screening protocols when aiming to detect colonization with carbapenemase-producing non-fermenting bacteria. Our results support the need for tailoring screening recommendations according to the bacterial species targeted.
View Article and Find Full Text PDFAn Overview of Monkeypox Virus Detection in Different Clinical Samples and Analysis of Temporal Viral Load Dynamics.
J Med Virol
December 2024
School of Technology and Management, Centre for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria, Leiria, Portugal.
Mpox is a zoonotic disease caused by the Monkeypox virus (MPXV), and since May 2022, tens of thousands of cases have been reported in non-endemic countries. We aimed to evaluate the suitability of different sample types for mpox diagnostic and assess the temporal dynamics of viral load. We evaluated 1914 samples from 953 laboratory-confirmed cases.
View Article and Find Full Text PDFPerformance and acceptability of self-collected specimens for diagnosis of rectal and pharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae infections among men who have sex with men in China: a randomized controlled trial.
BMC Infect Dis
November 2024
Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, 12 Jiangwangmiao Street, Nanjing, 210042, China.
Article Synopsis
- Extragenital Chlamydia trachomatis and Neisseria gonorrhoeae infections are common among men who have sex with men (MSM), and self-sampling may provide easier access to testing for those hesitant to visit health clinics.
- A study conducted in China compared the diagnostic accuracy of self-collected specimens to clinician-taken specimens, analyzing samples from 325 participants at six STI clinics.
- The findings demonstrated high agreement and sensitivity of self-sampling for both CT and NG infections, with 62% of MSM showing a preference for self-sampling, indicating it’s an acceptable alternative to traditional clinician-based testing.
[Analysis of risk factors for onset of acquired Serratia marcescens infection in neonatal intensive care unit].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
October 2024
Department of Neonatal Intensive Care Unit, Women and Children's Hospital of Ningbo University, Ningbo 315012, Zhejiang, China. Corresponding author: Li Yanhong, Email:
Objective: To analyze the clinical characteristics of critically ill neonates in the neonatal intensive care unit (NICU) who acquired Serratia marcescens infection for onset or colonization, and to explore the risk factors contributing to the onset of Serratia marcescens infection.
Methods: A retrospective case-control study was conducted by collecting clinical data from NICU neonates at the Women and Children's Hospital of Ningbo University between January 2017 and December 2023. Forty-four neonates with clinical signs and/or symptoms consistent with Serratia marcescens infection, and with Serratia marcescens isolated from specimens, would be enrolled as the infection onset group, while 45 neonates who tested positive for Serratia marcescens in rectal and/or pharyngeal cultures during the same period, but had no clinical signs or infection symptoms, were enrolled as the colonization control group.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!