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Augmented Reality-Assisted Microsurgery for Severe Thoracic Ossification of the Ligamentum Flavum: A Case Report.
Cureus
December 2024
Department of Orthopaedic Surgery, The Jikei University School of Medicine, Tokyo, JPN.
Ossification of the ligamentum flavum (OLF) can lead to dural ossification, significantly increasing the risk of complications, including intraoperative nerve injury. The application of augmented reality (AR) and advanced digital technologies in spine surgery has the potential to reduce these risks. This case report highlights a perioperative nerve injury-free microsurgery using elastic image fusion technology, which integrates preoperative imaging with intraoperative computed tomography for a patient with severe stenotic OLF and dural ossification.
View Article and Find Full Text PDFPer-Irradiation Monitoring by kV-2D Acquisitions in Stereotactic Treatment of Spinal and Non-Spinal Bony Metastases Using an On-Board Imager of a Linear Accelerator.
Cancers (Basel)
December 2024
Radiation Oncology Department, Centre Frederic Joliot, 76000 Rouen, France.
Background/objectives: An on-board imager on a linear accelerator allows the acquisition of kV-2D images during irradiation. Overlaying specific structures on these images enables the visual verification of movement at regular frequencies. Our aim was to validate this tracking method for the stereotactic treatment of bone metastases.
View Article and Find Full Text PDFCharacterizing the In Utero Phenome of the Chiari II Malformation-A Network Medicine Approach, Using Fetal MRI.
Prenat Diagn
January 2025
Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Objective: To apply a network medicine-based approach to analyze the phenome of the prenatal fetal MRI and biometric findings in the Chiari II malformation (CM II) to detect specific patterns and co-occurrences.
Method: A single-center retrospective review of fetal MRI scans obtained in fetuses with CM II was performed. Co-occurrence analysis was utilized to generate a phenotypic comorbidity matrix and visualized by Gephi software.
A novel network with enhanced edge information for left atrium segmentation from LGE-MRI.
Front Physiol
December 2024
School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China.
Introduction: Automatic segmentation of the left atrium (LA) constitutes a crucial pre-processing step in evaluating heart structure and function during clinical interventions, such as image-guided radiofrequency ablation of atrial fibrillation. Despite prior research on LA segmentation, the low contrast in medical images exacerbates the challenge of distinguishing various tissues, rendering accurate boundary delineation of the target area formidable. Moreover, class imbalance due to the small target size further complicates segmentation.
View Article and Find Full Text PDFA Defined Diet Combined with Sonicated Inoculum Provides a High Incidence, Moderate Severity Form of Experimental Autoimmune Encephalomyelitis (EAE).
ACS Pharmacol Transl Sci
December 2024
Synovo GmbH, Paul-Ehrlich-Straße 15, 72076 Tübingen, Germany.
Background: Myelin oligodendrocyte glycoprotein 35-55 (MOG)-peptide induced experimental autoimmune encephalomyelitis (EAE) is a model for inflammation of the brain and spinal cord. However, its severity and incidence vary within and between laboratories. Severe scores can lead to premature termination and are both unnecessary for readouts and detrimental to animal welfare.
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