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Oral theophylline corrects sinus node dysfunction in acute on chronic lithium toxicity: case report and systematic review of lithium-induced Sinus node dysfunction.
Front Cardiovasc Med
August 2024
Division of Cardiology, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
Article Synopsis
- Lithium can cause serious and often unreported cardiac issues like sinus node dysfunction (SND), which can lead to life-threatening conditions such as asystole.
- This study presents the first known successful use of Theophylline to correct SND resulting from lithium toxicity, alongside a systematic review of existing cases.
- Out of 1,117 reports, 49 studies showed that many patients experienced various degrees of SND; the majority recovered without lasting effects, though some required advanced medical interventions like pacemakers.
Lithium-Induced Hypercalcemia Presenting as Catatonia in a Patient With Schizoaffective Disorder.
Cureus
August 2023
Psychiatry, Jamaica Hospital Medical Center, Queens, USA.
Catatonia, a relatively rare and less explored consequence of lithium-induced hypercalcemia, represents a notable yet understudied side effect. Lithium is utilized in the management of acute mania and as a maintenance therapy for bipolar disorder. However, the specific catatonic presentation resulting from hypercalcemia remains poorly understood.
View Article and Find Full Text PDF[Lithium-induced nephrogenic diabetes insipidus during acute intoxication: a case report].
Pan Afr Med J
September 2023
Etablissement Public de Santé Ville Evrard, Neuilly sur Marne, France.
In case of dehydration, lithium can cause acute intoxication. This picture is mainly manifested by neurological disorders that can go as far as coma, digestive disorders, hydroelectrolytic disorders, and cardiovascular disorders. We report the case of a patient followed for bipolar disorder for 20 years and treated with lithium for 14 years and who presented an acute lithium intoxication resulting from a diabetes insipidus.
View Article and Find Full Text PDFLithium salts (lithium) is a psychotropic drug widely used as a pharmacological option in managing bipolar disorder. Regular monitoring of serum levels is necessary due to the narrow therapeutic range of lithium. Typically, the diagnosis of lithium intoxication is based on the presence of elevated plasma levels.
View Article and Find Full Text PDFLithium-Induced Bradycardia and Cardiomyopathy in a Patient With Bipolar Disorder and Paranoid Schizophrenia.
Cureus
June 2023
Cardiology, Providence VA Medical Center, Warren Alpert Medical School of Brown University, Providence, USA.
Lithium is primarily known to cause neurological and gastrointestinal side effects, however, cardiac effects have been rarely reported. We present a unique case of lithium cardiotoxicity causing bradyarrhythmia and cardiomyopathy. A 68-year-old man with a history of paranoid schizophrenia and bipolar disorder presented with altered mental status.
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