The register network of the German Society for Orthopaedics and Trauma (DGOU) consists of 14 registries that cover the various fields of traumatology and elective orthopedics. In addition to registries that focus on implants and types of diseases without age limitations, there are also registries dealing with special diseases in children and adolescents as well as the special needs of elderly patients with fractures. The registries serve as instruments for outcome research and quality assurance and can be used to develop treatment recommendations on a high level of evidence. The objective of the network is to exchange experience that facilitates the establishment of new registers, to pool expertise and to conserve resources.
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http://dx.doi.org/10.1007/s00113-016-0169-1 | DOI Listing |
J Prev (2022)
January 2025
Department of Health and Prevention, Institute of Psychology, University of Greifswald, Robert-Blum-Str. 13, 17489, Greifswald, Germany.
The digitalization of society increasingly blurs boundaries between analog and digital worlds, offering opportunities such as telemedicine and global connectivity through digital platforms. However, it also presents risks, including cyberbullying, addiction potential, harmful content, misinformation, and privacy concerns from data breaches and surveillance technologies. Social media, with its global reach, amplifies both opportunities for positive engagement and the responsibility to navigate largely unregulated content.
View Article and Find Full Text PDFPathologie (Heidelb)
January 2025
Institut für Pathologie, Universitätsmedizin Göttingen, Universität Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland.
After describing the anatomy of the spleen and the most important immunohistochemical stains for identifying cellular constituents of the normal splenic compartments, etiologies of splenomegaly and the diagnostic approach for spleen biopsies are discussed using the example of a North African patient with a recent migration background and sudden fever. The focus is on infectious diseases and the morphology and molecular features of hematolymphoid neoplasms, particularly the primary "splenic B‑cell lymphomas" according to the World Health Organization (WHO) classification. The importance of clinicopathological correlations and interdisciplinary cooperation in splenic pathology is emphasized.
View Article and Find Full Text PDFEur Cardiol
December 2024
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen Copenhagen, Denmark.
Despite significant advances in its management, AF remains a major healthcare burden affecting millions of individuals. Rhythm control with antiarrhythmic drugs or catheter ablation has been shown to improve symptoms and outcomes in AF patients, but current treatment options have limited efficacy and/or significant side-effects. Novel mechanism-based approaches could potentially be more effective, enabling improved therapeutic strategies for managing AF.
View Article and Find Full Text PDFFront Public Health
January 2025
Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Centre of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Childhood leukemia accounts for 30% of all pediatric cancer cases with acute lymphoblastic leukemia (ALL) being the most common subtype. Involvement of the gut microbiome in ALL development has recently garnered interest due to an increasing recognition of the key contribution the microbiome plays in maintaining the immune system's homeostatic balance. Commensal gut microbiota provide a first line of defense against different pathogens and gut microbiome immaturity has been implicated in ALL pathogenesis.
View Article and Find Full Text PDFJ Exp Biol
January 2025
Dartmouth College, Ecology, Evolution, Environment & Society Graduate Program, Hanover NH, USA.
Many animals communicate using call and response signals, but the evolutionary origins of this type of communication are largely unknown. In most cricket species, males sing and females walk or fly to calling males. In the tribe Lebinthini, however, males produce calls that trigger a vibrational reply from females, and males use the substrate vibrations to find the responding female.
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