In this study, four new lignan glucosides, named difengpiosides A-D (1-4), were isolated from the stem barks of Illicium difengpi, together with seven known compounds 5-11. Their structures were identified on the basis of spectroscopic analyses (1D and 2D NMR, HRESIMS, CD) and a comparison with literature data. All the compounds were evaluated for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cells.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273417 | PMC |
| http://dx.doi.org/10.3390/molecules21050607 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Arctiin alleviates the progression of osteoarthritis by regulating the cholesterol metabolic pathway.
Sci Rep
January 2025
Guangzhou First People's Hospital, the Second Affiliated Hospital, School of Medicine, South China University of Technology; Guangzhou First People's Hospital, Guangzhou Medical University, 1 Panfu Road, Yuexiu District, Guangzhou, 510180, China.
Osteoarthritis (OA) is a multi-factorial degenerative joint disease with unclear pathogenesis. Conservative treatments, primarily aimed at pain relief, fail to halt disease progression. Metabolic syndrome has recently been implicated in OA pathogenesis, underscoring the need for novel therapeutic strategies.
View Article and Find Full Text PDFSeed quality and relative lignan profiles of sesame prospected from northern Ghana.
Heliyon
October 2024
Institute of Applied Science and Technology, College of Basic and Applied Sciences, University of Ghana, Legon, Ghana.
The sesame seed contains oil, protein, dietary fibre, and several minerals and it is also a store of lignans. Lignans are key selection factors for sesame quality due to their health, nutritive and market value. In Ghana sesame growers rely on wild or undocumented planting seeds which are of mixed colouration and its lignan content is ambiguous.
View Article and Find Full Text PDFSecondary Metabolites and Their Biological Evaluation from the Aerial Parts of Sibth. & Sm. (Asteraceae).
Int J Mol Sci
October 2024
Laboratory of Pharmacognosy, Faculty of Health Sciences, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Phytochemical investigation of Sibth. & Sm. resulted in the isolation of twenty-two natural products: eleven sesquiterpene lactones, artemorin (), tamirin (), tanachin (), reynosin (), baynol C (), desacetyl-β-cyclopyrethrosin (), 1β-hydroxy-4α-methoxy-5α,7α,6β-eudesm-11(13)-en-6,12-olide (), 1β,4α,6α-trihydroxyeudesm-11-en-8α,12-olide (), 1β-hydroxy-arbusculin A (), methyl-1β,4α,6α-trihydroxy-5α,7αH-eudesm-11(13)-en-12-oate () and methyl-1β,6α,8α-trihydroxy-5α,7αH-eudesma-4(15),11(13)-dien-12-oate (); one lignan, pinoresinol (); one norisoprenoid, loliolide (); six flavonoids (four genins and two glycosides), hispidulin (), nepetin (), jaceosidin (), eriodictyol (), eriodictyol-3'-O-β-D-glucoside () and eriodictyol-7-O-β-D-glucuronide (); and three phenolic derivatives (one phenolic acid and two phenolic glucosides), protocatechuic acid (), arbutin () and nebrodenside A ().
View Article and Find Full Text PDFPreliminary study on the association between lignan metabolites and CT non-destructive testing of coconut fruit at different developmental stages.
PeerJ
September 2024
Coconut Research Institute, Chinese Academy of Tropical Agricultural Sciences/Hainan Key Laboratory of Tropical Oil Crops Biology, Wenchang, Hainan, China.
Lignans play a crucial role in maintaining plant growth, development, metabolism and stress resistance. Computed tomography (CT) imaging technology can be used to explore the internal structure and morphology of plants, and understanding the correlation between the two is highly significant. In this study, the content of lignan metabolites in coconut water was determined using liquid chromatography.
View Article and Find Full Text PDFDietary secoisolariciresinol diglucoside crude extract improves growth through modulating rumen bacterial community and epithelial development in lambs.
J Sci Food Agric
January 2025
Ruminant Nutrition and Feed Engineering Technology Research Centre, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Background: Flaxseed lignans, types of polyphenolic compounds, primarily consist of secoisolariciresinol diglucoside (SDG). Natural plant extracts are becoming increasingly important as feed for ruminant animals. An underutilized plant bioactive component, SDG shows promising benefits for young ruminant production.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!