AI Article Synopsis

  • Renal failure is common in cirrhosis patients, especially with ascites, often due to reduced blood flow impacting kidney function.
  • Hepatorenal syndrome (HRS) is a specific type of kidney failure linked to liver cirrhosis or severe liver failure, marked by abnormal blood vessel responses.
  • HRS is classified into two types: type 1 and type 2, based on the severity of kidney failure in these patients.

Article Abstract

Renal failure commonly occurs in patients affected by cirrhosis, especially when there is ascites. It is typically secondary to intercurrent events that can further compromise blood flow in conditions of relatively decreased renal perfusion. Hepatorenal syndrome (HRS) is a particular and common type of kidney failure that affects patients with liver cirrhosis or, less frequently, with fulminant hepatic failure. The syndrome is characterized by splanchnic vasodilation and renal vasoconstriction. The classification of HRS identifies 2 categories of kidney failure, known as type 1 and type 2 HRS, that occur in patients with either cirrhosis or fulminant hepatic failure.

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http://dx.doi.org/10.1159/000445465DOI Listing

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