Objectives: Although several previous studies have reported that a ventricular septal defect (VSD) can be closed safely through the detached tricuspid valve (TV) without impairing TV function, this has not been demonstrated for infants younger than 3 months.
Methods: We enrolled 296 infants younger than 3 months who underwent VSD closure through the right atrium between January 2004 and December 2013. In the study group of 49 patients (16.6%), the TV was detached for better exposure of the defect.
Results: The median age and weight were 63.5 days (14-90 days) and 4.4 kg (2.1-6.7 kg), without intergroup differences. Abnormal chordal attachment of the TV in preoperative echocardiography was associated with detachment of the TV during surgery (P = .001). Cardiopulmonary bypass (P = .001) and aortic crossclamp (P < .001) times were significantly longer in the study group. A permanent pacemaker was required for 2 patients in the control group. Follow-up echocardiography was available for 282 patients at a median of 21 months (1-108 months) after the operation. On final echocardiography, tricuspid regurgitation greater than grade 2 was observed in 1 patient in the study group and residual VSD existed in 4 patients (1 in the study group), without statistical significance.
Conclusions: Detachment of the TV can be used safely for better exposure of the VSD without increased risk of tricuspid regurgitation in infants younger than 3 months. Preoperative echocardiography might be useful for predicting the possibility of detachment of the TV for enhancing exposure of the VSD.
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http://dx.doi.org/10.1016/j.jtcvs.2016.03.067 | DOI Listing |
Int J Gynaecol Obstet
December 2024
Department of Midwifery, Faculty of Health Sciences, Istanbul Atlas University, İstanbul, Türkiye.
Objective: This study aimed to examine the parenting behaviors of mothers and fathers during the postpartum period.
Methods: This descriptive cross-sectional study was conducted on 200 married individuals who had healthy babies between February 2019-September 2020 at a hospital. This study used introductory information forms for parents, "Postpartum Parenting Behavior Scale (PPBS)" and "Marital Adjustment Scale (MAS)".
Iran J Kidney Dis
December 2024
Pediatric Nephrology Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Introduction: Acute kidney injury (AKI) is a frequent complication after hematopoietic stem cell transplantation (HSCT), with reported incidences ranging from 20-70% within the first 100 days post-transplant. AKI can adversely impact outcomes and survival in this patient population.
Methods: This retrospective study evaluated 110 pediatric patients who underwent HSCT at Mofid Children's Hospital, affiliated with Shahid Beheshti University of Medical Sciences, Tehran, Iran, between 2016-2021.
Ann Child Neurol Soc
June 2024
Division of Neurology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Objective: Tuberous sclerosis complex (TSC) results from overactivity of the mechanistic target of rapamycin (mTOR). Sirolimus and everolimus are mTOR inhibitors that treat most facets of TSC but are understudied in infants. We sought to understand the safety and potential efficacy of preventative sirolimus in infants with TSC.
View Article and Find Full Text PDFJAMA Netw Open
December 2024
Center of Excellence in Maternal, Child and Adolescent Health, University of California, Berkeley.
Importance: With disparate Black maternal health outcomes in the US and a steadily expanding non-US-born Black population, it is beneficial to investigate Black maternal health outcomes by country of origin.
Objective: To compare the prevalence of maternal morbidity and infant birth outcomes between US-born and non-US-born Black populations in the US.
Design, Setting, And Participants: This cross-sectional study included all registered hospital births in the US from the 2021 National Vital Statistics Systems (NVSS) Natality Data.
Background: Remission is the desired outcome following OIT as it allows individuals to discontinue treatment and eat the allergen freely. Early initiation of OIT in infants and toddlers has been embraced as an approach to increase the likelihood of remission. However, there is no high-quality evidence supporting younger age as an independent factor driving remission; available studies are limited by small samples of younger subjects and lack of adjustment for confounding covariates, particularly peanut-specific IgE (sIgE) levels which is closely correlated with age.
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