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Feasibility and Efficacy of a Novel Mindfulness App Used With Matcha Green Tea in Generally Healthy Adults: Randomized Controlled Trial.
JMIR Mhealth Uhealth
December 2024
Saga Nutraceuticals Research Institute, Otsuka Pharmaceutical Co Ltd, Saga, Japan.
Background: Mindfulness practices, such as breathing meditation (BM), reduce stress and enhance mood. One such practice is mindful eating, where a practitioner focuses on the five senses while eating or drinking. A novel set of prototypes has been developed, incorporating principles of mindful eating.
View Article and Find Full Text PDFAddisonian Pigmentation - The Great Mimicker - A Review.
Indian J Dermatol
October 2024
Department of Radiology, Institute of Liver and Biliary Sciences, New Delhi, India.
Skin colour usually depends upon melanin, haemoglobin, and carotenoids. Pigmentary disorders indicate an increased amount of melanin, leading to a darker colour of the skin, called hypermelanosis. Addison's disease is a rare endocrinal disorder with severe oral and systemic manifestations.
View Article and Find Full Text PDFThe role of nutrition-related clinical trials in informing dietary recommendations for health and treatment of diseases.
J Clin Lipidol
October 2024
Midwest Biomedical Research, Addison, IL, United States; Indiana University School of Public Health, Bloomington, IN, United States.
Dietary guidance is based on a robust evidence base that includes high-quality clinical trials, of which some have been designed to establish causal relationships between dietary interventions and ASCVD risk reduction. However, the complexity associated with conducting these trials has resulted in criticism of nutrition and dietary recommendations because the strength and quality of evidence falls short of that for some pharmaceutical interventions. In this paper, we aim to promote greater awareness of the nutrition-related clinical trials that have been conducted showing ASCVD benefits and how this evidence has contributed to dietary recommendations.
View Article and Find Full Text PDFStatin-Associated Muscle Symptoms: Identification and Recommendations for Management.
Curr Atheroscler Rep
November 2024
Emory Department of Medicine, Lipid Clinic and Cardiovascular Risk Reduction Program, Emory University, Atlanta, GA, USA.
Article Synopsis
- Statins are the primary medication for lowering bad cholesterol (LDL), but some patients experience muscle-related side effects known as statin-associated muscle symptoms (SAMS).
- Recent guidelines from organizations like the National Lipid Association provide strategies for doctors to identify and manage patients with SAMS, as this is the most common reason for statin intolerance.
- Many patients can still tolerate some statin therapy, and when combined with non-statin medications, an effective treatment plan can be created through open discussions between clinicians and patients to lower the risk of heart disease.
Pembrolizumab, a PD-1 inhibitor, has become a cornerstone in the treatment of various cancers, including breast cancer. However, its use is associated with immune-related adverse effects (irAEs), particularly those involving the endocrine system. This case report presents a rare instance of pembrolizumab-induced Addison's disease leading to severe hyponatremia.
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