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Predictive Value of Varicocele Grade and Histopathology in Simultaneous Varicocelectomy and Sperm Retrieval in Non-Obstructive Azoospermia: A Retrospective Cohort Study.
Medicina (Kaunas)
December 2024
Laboratory of Spermatology, Department of Urology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece.
Varicocele repair in men with non-obstructive azoospermia (NOA) remains a subject of debate due to inconsistent outcomes. This study aimed to evaluate the impact of microsurgical varicocelectomy on sperm recovery rates in men with NOA and to assess the role of varicocele grade and testicular histopathology in predicting postoperative outcomes. A retrospective cohort study was conducted of 78 men diagnosed with NOA and clinical varicocele who underwent microsurgical subinguinal varicocelectomy with simultaneous diagnostic and therapeutic testicular biopsy at the Department of Urology of the University of Ioannina between September 2013 and December 2021.
View Article and Find Full Text PDFAssessing the outcomes of subinguinal microsurgical varicocelectomy: pulling technique compared to the conventional method.
Int Urol Nephrol
December 2024
Department of Urology, University of Istanbul, Faculty of Medicine, Istanbul, Turkey.
Introduction: The positive effect of varicocelectomy on sperm parameters (sperm morphology, concentration, motility) and fertility and pregnancy rates has been proven. Although various techniques have been defined for varicocele treatment, varicocelectomy with the pulling technique was first defined in 2017. The aim of this retrospective study is to compare the effectiveness and reliability of subinguinal microsurgical varicocelectomy with the "pulling" technique and conventional subinguinal varicocelectomy.
View Article and Find Full Text PDF[Recurrent varicocele: causes and treatment].
Urologiia
July 2024
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Moscow, Russian Federation.
Introduction: Among the different options for varicocele surgery, microsurgical varicocelectomy demonstrates the best results, but a relapse is subsequently detected in 1-3% of cases. It was previously believed that the cause of recurrence lies in the presence of various sources of venous outflow from the testicle, but recent studies show that the collaterals of the gonadal vein are the main reason of recurrence.
Purpose Of The Study: to determine the leading cause of recurrence, to evaluate the effectiveness and optimal surgical tactics depending on the method of primary treatment.
Aim: To evaluate the effect of microsurgical subinguinal varicocelectomy on sperm DNA fragmentation (SDF) in patients with elevated SDF levels (more than 15%) and clinical varicocele.
Materials And Methods: A single-center, retrospective, observational, uncontrolled study was carried out. The results of a survey of 33 patients with clinical varicocele, infertility or recurrent miscarriage and sperm DNA fragmentation of more than 15% were analyzed.
[Cryopreservation of human spermatozoa or testicular tissue for fertility preservation].
Urologie
November 2024
Abteilung für Klinische und Operative Andrologie, Centrum für Reproduktionsmedizin und Andrologie, WHO-Kooperationszentrum, EAA-Ausbildungszentrum, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, Gebäude D11 (Domagkstraße 11), 48149, Münster, Deutschland.
Loss of reproductive capacity due to treatments for malignant or non-malignant diseases or even as a result of diseases themselves significantly impacts patients' quality of life. Cryopreservation of sperm from ejaculate is a well-established procedure for preserving the fertility of these patients and thus improving their quality of life in the long term. If cryopreservation of sperm from ejaculate is not possible, either because ejaculation cannot occur or no sperm can be found in the ejaculate, the preferred treatment option is (microsurgical) testicular sperm extraction (mTESE).
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