Fungal infections constitute a diverse spectrum of infections with variable clinical and imaging features. They are commonly opportunistic infections that affect immunocompromised individuals secondary to inherited or acquired disorders. Fungal infections may affect multiple organ systems and contribute to significant morbidity and mortality. Although the imaging features of some fungal infections are characteristic and permit their diagnosis, many mycotic infections manifest nonspecific findings. Definitive diagnosis often depends on histopathological analysis. Early diagnosis requires both clinical suspicion and supporting radiological evidence. Early treatment results in reduced morbidity and mortality. This article reviews the imaging findings in opportunistic and endemic fungal infections.
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http://dx.doi.org/10.1016/j.rcl.2015.12.002 | DOI Listing |
Front Oral Health
January 2025
Department of Stomatology, Ren Ai Community Healthcare Center of Longquanyi District, Chengdu, Sichuan, China.
The morbidity of oral disorders, including gingivitis, caries, endodontic-periodontal diseases, and oral cancer, is relatively high globally. Pathogenic cells are the root cause of many oral disorders, and oral therapies depend on eradicating them. Photodynamic therapy (PDT) has been established as a potential and non-invasive local adjuvant treatment for oral disorders.
View Article and Find Full Text PDFAccess Microbiol
January 2025
Department of Microbiology, Lady Hardinge Medical College & Associated Hospitals, New Delhi, Delhi, India.
Coronavirus disease 2019 (COVID-19) pandemic has been prevailing for more than a year, associated with an increased number of opportunistic invasive fungal infections in patients who have been critically ill or immunocompromised. In this retrospective study, details of various clinical specimens received from suspected patients of fungal infections were studied. Fungal cultures were positive in 64% (51 out of 79) of COVID-19-positive patients and 43% (163 out of 381) of COVID-19-negative patients during the second wave of COVID-19 in 2021.
View Article and Find Full Text PDFSovrem Tekhnologii Med
January 2025
MD, PhD, Ophthalmologist; Privolzhsky District Medical Center of Federal Medico-Biologic Agency of Russia, 14 llyinskaya St., Nizhny Novgorod, 603000, Russia; Assistant, Department of Eye Diseases; Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
Unlabelled: is to develop a method for diagnosing fungal keratitis based on the analysis of photographs of the anterior segment of the eye using deep learning algorithms with subsequent evaluation of sensitivity and specificity of the method on a test data set in comparison with the results of practicing ophthalmologists.
Materials And Methods: The study has included the stages of data acquisition, image pre-training and markup, selection of training approach and neural network architecture, training with input data augmentation, validation with hyperparameter correction, evaluation of algorithm performance on a test sample, and determination of sensitivity and specificity of fungal keratitis detection by practicing doctors. A total of 274 anterior segment images were used, including 130 photographs of the eyes affected by fungal keratitis and 144 photographs illustrating normal eyes, keratitis of other etiologies, and various anterior segment pathologies.
Expert Rev Anti Infect Ther
January 2025
3rd Department of Critical Care, Evgenidio Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Introduction: Fungal infections constitute a significant global health threat, with an estimated incidence of 6.5 million invasive fungal infections and 2.5 million associated deaths each year.
View Article and Find Full Text PDFSjogren's syndrome (SS) is a chronic inflammatory autoimmune disease characterized by exocrine gland dysfunction. Mucormycosis is a rare yet life-threatening opportunistic fungal infection caused by species, with a high mortality rate. In patients undergoing long-term immunosuppressive therapy or corticosteroid use, especially when compounded by conditions such as diabetes or hyperlipidemia, Mucor can become pathogenic.
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