Background: Reconstruction of cranial defects due to trauma or other causes has been carried out since ages with a wide variety of materials. The aim of reconstruction was mainly to restore cosmesis and protect the brain from further injury. However, recent studies have shown that cranioplasty not only improves the cerebral blood flow but also leads to improvement of cognitive functions. The materials used include autologous bone, allogeneic bone, xenografts, and alloplasts. The search for an ideal material continues. The authors present their experience with cranioplasty using prefabricated porous polyethylene implants.
Materials And Methods: Patients requiring cranioplasty for reconstruction of large sized (more than 15 cm in any 1 dimension) cranial defects were selected. Three patients were men and 2 were women. The age group of the patient ranged from 18 to 58 years. Preformed Biopore Hemisphere was used in every patient for cranial reconstruction.
Results: No complications were seen in our patients. One patient who had undergone titanium cranioplasty previously showed remarkable improvement in cognitive functions.
Conclusion: Porous polyethylene prefabricated implants are a good restorative material for reconstruction of large cranial defects.
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http://dx.doi.org/10.1097/SCS.0000000000002480 | DOI Listing |
Clin Oral Investig
January 2025
Division of Prosthodontics and Implant Prosthodontics, Department of Surgical Sciences, University of Genova, Genova, Italy.
Objectives: The present systematic review aimed to evaluate if cortical bone perforation is effective in enhancing periodontal surgery and guided bone regeneration (GBR) in humans.
Materials And Methods: Electronic search was performed in PubMed, Scopus and Cochrane CENTRAL up to October 31st, 2023. Grey literature was also searched.
Neuropediatrics
January 2025
Neonatology, Leiden University, Leiden, Netherlands.
Background Hemimegalencephaly (HME) is a rare congenital disorder that is initiated during embryonic development with abnormal growth of one hemisphere. Tuberous sclerosis complex (TSC), a genetic disorder, is rarely associated with HME. Methods We present a case of a newborn with HME with a confirmed mutation in the TSC-1 gene and describe the clinical course, findings on (amplitude integrated) electroencephalography (aEEG), cranial ultrasound (CUS), MRI, and the postmortem evaluation.
View Article and Find Full Text PDFJ Appl Oral Sci
January 2025
Universitas Airlangga, Faculty of Dental Medicine, Department of Oral Biology, Surabaya, East Java, Indonesia.
Unlabelled: Guided bone regeneration (GBR) is an alternative treatment for craniofacial bone defects reconstruction through membrane barrier adaptation, such as demineralized dentin material membrane (DDMM). DDMM is used as a substitute for GBR material, which aligns with Green Economy principles, it has a good biological osteoinductive and osteoconductive effects, and its structure resembles bones. The balance of bone remodeling when experiencing craniofacial defects will be altered and allow changes to resorption activity, so the mechanisms of osteoclastogenesis and bone resorption are vital.
View Article and Find Full Text PDFTunis Med
January 2025
Department of embryo-fetopathology, La Rabta Maternity and Neonatology Center, El Manar II University, 1007 Tunis, Tunisia.
Introduction: Anencephaly is a serious developmental defect of the central nervous system in which the brain and cranial vault are grossly malformed. The cerebrum and cerebellum are reduced or absent, but the hindbrain is present. Anencephaly is a part of the neural tube defect spectrum.
View Article and Find Full Text PDFCranioplasty is an operation that aims to repair a defect in the skull. Indications commonly include Traumatic Brain Injury (TBI), tumours, and infections. It carries a high rate of postoperative morbidity.
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