AI Article Synopsis

  • Orbital lymphoma is a rare type of cancer that usually gets found early, but about 33% of people can end up with it spreading to other places.
  • A 63-year-old man had this type of lymphoma in both his eyes and started treatment with chemotherapy and radiation, which worked at first.
  • Sadly, after his second treatment, he had severe stomach bleeding and passed away two months later, but the doctors found that only his adrenal glands were affected by the lymphoma, not other organs.

Article Abstract

Orbital lymphoma is very rare malignant neoplasm, usually diagnosed in early stage of disease as primary lymphoma, but dissemination occurs in approximately 33% of cases. Isolated bilateral adrenal lymphomatous involvement is extremely rare, described in 0.83% of cases. We present autopsy case of a 63-year-old man with bilateral orbital diffuse large cell lymphoma, clinical stage IEA, successfully treated by one cycle of chemo- and radiotherapy, but after administration of the second cycle, the patient developed signs of gastrointestinal hemorrhage and died two months after the diagnosis. Autopsy findings exclude lymphoma involvement of any organ except histopathological infiltration of both adrenal glands without evidence of a mass lesion.

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