Due to a high number of accidents at work, actions have been undertaken to apply numerical simulation for reconstruction of their course in time. First works on this issue showed that the numerical human body model developed in the Central Institute for Labour Protection - National Research Institute (CIOP-PIB) should be adjusted to the nature of specific accidents. Hence, a need arose to adjust the model for reconstruction and simulation of falls from heights. The adjustment involved supplementing the model with functions enabling taking into account movements of a person at the time of losing their balance, as such movements influence the course of a fall. For this purpose, a study with participation of volunteers has been conducted to define these movements. Within the framework of the study, reactions (body movements) of the subjects at the time of losing their balance were recorded. The works resulted in obtaining parameters that, after an analysis, may be used as initial conditions for a numerical model of the human body.
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Sci Rep
December 2024
Faculty of Civil Engineering and Resource Management, AGH University of Krakow, Krakow, Poland.
Continuous professional development of university employees is crucial to implementing the mission of higher education institutions. University staff work includes various activities related to teaching, research studies, and cooperation with the industrial sector. It motivated authors to identify crucial areas and skills that should be developed at the academic level.
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December 2024
School of Public Health, Shandong Second Medical University, 7166 Baotong West Street, Weifang, Shandong, China.
Background: Studies on acceptance of cosmetic surgery may not be cross-culturally invariant, but little is known about it in non-Western populations. Therefore, it is necessary to develop cross-cultural research on it.
Methods: 230 international students in China aged 18-27 years (M = 21.
Sci Rep
December 2024
Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.
Despite decades of improvements in cytotoxic therapy, the current standard of care for locally advanced pancreatic cancer (LAPC) provides, on average, only a few months of survival benefit. Stereotactic Body Radiation Therapy (SBRT), a technique that accurately delivers high doses of radiation to tumors in fewer fractions, has emerged as a promising therapy to improve local control of LAPC; however, its effects on the tumor microenvironment and hypoxia remain poorly understood. To explore how SBRT affects pancreatic tumors, we combined an orthotopic mouse model of pancreatic cancer with an intravital microscopy platform to visualize changes to the in vivo tumor microenvironment in real-time.
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December 2024
Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
The cytokine homologs, particularly transforming growth factor (TGF)-β, is a crucial immunomodulatory molecule and involved in growth and developmental processes in several helminths. In this study, the basic properties and functions of T. spiralis TGF-β homolog 2 (TsTGH2) were characterized using bioinformatics and molecular biology approaches.
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December 2024
Geriatric Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
The relationship between the weight-adjusted waist circumference index (WWI) and the senescence-inhibitory protein Klotho remains unknown. Therefore, this study aimed to investigate the relationship between WWI and soluble Klotho (s-Klotho). This study analyzed 9,928 participants based on the 2007-2016 National Health and Nutrition Examination Survey (NHANES).
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