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Association Between Serum Levels of Vitamin D and the Risk of Post-Stroke Anxiety. | LitMetric

Association Between Serum Levels of Vitamin D and the Risk of Post-Stroke Anxiety.

Medicine (Baltimore)

From the Department of Neurology (CW, WR, JC, BZ, QJ, LW, CC, LZ, YC, YG, JZ, DL, BS, JH), The First Affiliated Hospital of Wenzhou Medical University and Department of Neurology, Ruian People's Hospital, Wenzhou (SZ), People's Republic of China.

Published: May 2016

AI Article Synopsis

Article Abstract

Low levels of serum vitamin D are common in patients with mood disorders and stroke. It has been shown that low levels of serum vitamin D indicate a risk of depression in post-stroke subjects. Our aim was to determine the relationship between vitamin D and post-stroke anxiety (PSA).A consecutive series of 226 first acute ischemic stroke patients were recruited and followed up for 1 month. Serum levels of vitamin D were measured within 24 hours of admission. Patients with significant clinical symptoms of anxiety and a Hamilton anxiety scale score >7 were diagnosed as having PSA. In addition, 100 healthy subjects were recruited as controls and underwent measurements of serum vitamin D.A total of 60 patients (26.55%) showed anxiety at 1 month. Both PSA patients and non-PSA patients had lower serum levels of vitamin D than healthy subjects. A significant relationship was found between PSA and serum levels of vitamin D. Low serum levels of vitamin D (≤38.48 nmol/L) were independently associated with the development of PSA (OR: 2.49, 95% CI: 1.21-5.13, P = 0.01).Serum vitamin D status is related to the occurrence of anxiety in post-stroke patients and may be an independent risk factor of PSA after 1 month.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863794PMC
http://dx.doi.org/10.1097/MD.0000000000003566DOI Listing

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