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DigiLoCS: A leap forward in predictive organ-on-chip simulations.
PLoS One
January 2025
ESQlabs Gmbh, Saterland, Germany.
Digital twins, driven by data and mathematical modelling, have emerged as powerful tools for simulating complex biological systems. In this work, we focus on modelling the clearance on a liver-on-chip as a digital twin that closely mimics the clearance functionality of the human liver. Our approach involves the creation of a compartmental physiological model of the liver using ordinary differential equations (ODEs) to estimate pharmacokinetic (PK) parameters related to on-chip liver clearance.
View Article and Find Full Text PDFTopochemical Synthesis and Electronic Structure of High-Crystallinity Infinite-Layer Nickelates on an Orthorhombic Substrate.
Nano Lett
January 2025
Department of Physics, Hong Kong Institute for Advanced Study, City University of Hong Kong, Kowloon, Hong Kong 999077, China.
Superconductivity in infinite-layer nickelates has stirred much research interest, to which questions regarding the nature of superconductivity remain elusive. A critical leap forward to address these intricate questions is through the growth of high-crystallinity infinite-layer nickelates, including the "parent" phase. Here, we report the synthesis of a high-quality thin-film nickelate, NdNiO.
View Article and Find Full Text PDFAll-solid-state Li-ion batteries (ASSBs) represent a promising leap forward in battery technology, rapidly advancing in development. Among the various solid electrolytes, argyrodite thiophosphates Li6PS5X (X = Cl, Br, I) stand out due to their high ionic conductivity, structural flexibility, and compatibility with a range of electrode materials, making them ideal candidates for efficient and scalable battery applications. However, despite significant performance advancements, the sustainability and recycling of ASSBs remain underexplored, posing a critical challenge for achieving efficient circular processes.
View Article and Find Full Text PDFOptimizing inpatient diabetes management with the diabetes dashboard.
JBI Evid Implement
January 2025
Queensland Digital Health Centre, Centre for Health Services Research, Faculty of Medicine, The University of Queensland, Brisbane, Qld, Australia.
Abstract: Inpatient diabetes management presents a complex challenge that is distinct from outpatient management. This is due to acute changes in physiology, medication regimens, and eating patterns associated with hospitalization, alongside the condition's prevalent and variable nature. The conventional systems for managing glycemic control in hospital have been found lacking, with gaps in data integration, decision support, and timely intervention.
View Article and Find Full Text PDFPhotonic crystal fiber sensors in the THz domain: A leap forward in alcohol detection.
Heliyon
December 2024
Department of Electrical and Electronic Engineering, Pabna University of Science and Technology, Pabna, 6600, Pabna, Bangladesh.
Article Synopsis
- Methanol is a toxic substance used in industrial applications, while ethanol is safe for consumption and commonly found in beverages and antiseptics.
- A new Photonic Crystal Fiber (PCF) sensor has been developed to accurately detect both methanol and ethanol, achieving high relative sensitivities of 95.72% and 97.55%, respectively.
- This sensor offers exceptional precision and low material loss, enhancing safety monitoring and quality control in industries that use these substances.
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