With Golgi impregnation, a simple amacrine cell type is described in the chick retina. The most relevant morphological feature of these retinal neurons is a single straight, radial trunk which dichotomizes tangentially in a rectilinear expansion in the 5th stratum of the inner plexiform layer (IPL).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/02713688908995187 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Broadband Long Wavelength Light Promotes Myopic Eye Growth and Alters Retinal Responses to Light Offset in Chick.
Invest Ophthalmol Vis Sci
January 2025
School of Psychology and Public Health, La Trobe University, Melbourne, Australia.
Purpose: Prolonged exposure to broadband light with a short-wavelength (blue) or long-wavelength (orange/red) bias is known to impact eye growth and refraction, but the mechanisms underlying this response are unknown. Thus, the present study investigated the effects of broadband blue and orange lights with well-differentiated spectrums on refractive development and global flash electroretinography (gfERG) measures of retinal function in the chick myopia model.
Methods: Chicks were raised for 4 days with monocular negative lenses, or no lens, under blue, orange, or white light.
A Novel De Novo Missense Variant in Netrin-1 (NTN1) Associated With Chorioretinal Coloboma, Sensorineural Hearing Loss and Polydactyly.
Clin Genet
December 2024
Development, Ageing and Disease, UCL Institute of Ophthalmology, London, UK.
Microphthalmia, anophthalmia and coloboma (MAC) comprise a highly heterogeneous spectrum of congenital ocular malformations with an estimated incidence of 1 in 5000 to 1 in 30 000 live births. Although there is likely to be a genetic component in the majority of cases, many remain without a molecular diagnosis. Netrin-1 was previously identified as a mediator of optic fissure closure from transcriptome analyses of chick and zebrafish and was shown to cause ocular coloboma when knocked out in both mouse and zebrafish.
View Article and Find Full Text PDFRegulating the formation of Müller glia-derived progenitor cells in the retina.
Glia
January 2025
Department of Neuroscience, College of Medicine, The Ohio State University, Columbus, Ohio, USA.
We summarize recent findings in different animal models regarding the different cell-signaling pathways and gene networks that influence the reprogramming of Müller glia into proliferating, neurogenic progenitor cells in the retina. Not surprisingly, most of the cell-signaling pathways that guide the proliferation and differentiation of embryonic retinal progenitors also influence the ability of Müller glia to become proliferating Müller glia-derived progenitor cells (MGPCs). Further, the neuronal differentiation of MGPC progeny is potently inhibited by networks of neurogenesis-suppressing genes in chick and mouse models but occurs freely in zebrafish.
View Article and Find Full Text PDFDynamic BMP gene expression regulation in chick RPE during recovery from short term optical defocus and form-deprivation.
PLoS One
October 2024
Herbert Wertheim School Optometry and Vision Science, University of California, Berkeley, California, United States of America.
Article Synopsis
- - The study focused on how chick retinal pigment epithelium (RPE) gene expression of BMPs (Bone Morphogenetic Proteins) changes during recovery after short-term optical treatments, including lens wear and form deprivation.
- - White-Leghorn chicks were subjected to different lenses or diffusers for various durations, and then their recovery was monitored in terms of refractive errors and changes in choroidal thickness (ChT) over 96 hours.
- - Key findings indicated that BMP2 gene expression significantly increased with +10 D lens treatment shortly after application, while -10 D and form deprivation treatments led to a decrease in BMP2 expression, with recovery times being notably different between treatments.
Administration of Nicotine Can Inhibit Myopic Growth in Animal Models.
Invest Ophthalmol Vis Sci
September 2024
Centre for Research in Therapeutic Solutions, Faculty of Science and Technology, University of Canberra, Bruce, Canberra, Australia.
Purpose: While previously investigating the mechanism by which atropine inhibits ocular growth, we observed that stimulation of nicotinic receptors can inhibit experimental myopia. This study expands on that preliminary finding and investigates the safety and efficacy of nicotinic stimulation in the inhibition of ocular growth.
Methods: Nicotine's ability to inhibit form-deprivation myopia (FDM), following intravitreal injection (9 chicks per group) or topical application (6 chicks per group), was investigated over three doses.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!