AI Article Synopsis
- * There are various other skin and systemic diseases linked to DUH, and recent research has identified a mutation in the ABCB6 protein that may explain the pigment changes.
- * A new case has been reported connecting DUH with primary ovarian failure and hypothyroidism, adding to the known associations of this condition.
Article Abstract
Dyschromatosis Universalis Hereditaria (DUH) belongs to a group of congenital diffuse reticulate pigmentary disorders characterised by both hypo and hyper pigmented macules. It is both hereditary and sporadic. A number of associated cutaneous and systemic diseases have been reported. The recent discovery of the mutation in ATP binding cassette protein, ABCB6 in DUH attempts to explain the reason behind the pigmentary abnormalities and varied associations. We add a new association by reporting a case of DUH with primary ovarian failure (POF) and hypothyroidism.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843368 | PMC |
| http://dx.doi.org/10.7860/JCDR/2016/17525.7368 | DOI Listing |
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