[Purpose] The purpose of this study was to investigate the immediate effect of proprioceptive neuromuscular facilitation on muscle tone and muscle stiffness in stroke patients. [ Subjects and Methods] The subjects consisted of 15 patients with chronic stroke (stroke group) and 15 healthy persons (healthy group). We measured the effects of proprioceptive neuromuscular facilitation intervention on the lower extremity using a muscle tone measurement device; this detected changes in muscle tone and stiffness in the lower extremity muscles. [Results] Measurements taken before the intervention showed that, on average, the lower extremity muscles of the stroke group showed abnormally increased muscle tone and stiffness compared to the lower extremity muscles of the healthy group. After the intervention, the average muscle tone and stiffness in the lower extremity muscles of the stroke group decreased, but this change was insignificant, and the differences between the two groups were also insignificant. [Conclusion] Based on the findings of this study, we recommend proprioceptive neuromuscular facilitation treatment of both affected and non-affected sides to decrease the abnormally increased muscle tone and stiffness in the lower extremity muscles of chronic stroke patients.
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http://dx.doi.org/10.1589/jpts.28.967 | DOI Listing |
J Hypertens
December 2024
Institute for Fetology, The First Affiliated Hospital of Soochow University, Jiangsu.
Background: Paternal preconception alcohol exposure affects fetal development; however, it is largely unknown about the influences on offspring vasculature and mechanisms.
Methods: Offspring born form paternal rats treated with alcohol or water before pregnant was raised until 3 months of age. Vessel tone of mesenteric arteries was detected using myograph system; whole-cell calcium channel current in smooth muscle cells was tested using patch-clamp; molecule expressions were detected with real-time PCR, western blotting, and Dihydroethidium (DHE); DNA methylations were determined using targeted bisulfate sequencing assay.
Am J Phys Med Rehabil
February 2025
From the Centre for Translational Medicine, Semmelweis University, Budapest, Hungary (OZG, MV, MAE, LS, ZM, PH, TT); Department of Orthopaedics, Semmelweis University, Budapest, Hungary (OZG, MV, TT); Department of Anesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary (ZM); Department of Anesthesiology and Intensive Therapy, Poznan University for Medical Sciences, Poznan, Poland (ZM); and Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary (PH).
Objectives: This systematic review and meta-analysis of randomized controlled trials aimed to summarize the reported functional effects of upper limb botulinum toxin treatment in children with spastic cerebral palsy.
Design: Six databases were searched in October 2022. Two independent authors screened and extracted data on upper limb function, body function, life quality, muscle tone, spasticity, goals, pain, adverse events, and client satisfaction.
Int Urogynecol J
January 2025
Department of Rehabilitation Medicine, First Affiliated Hospital of Gannan Medical University, No. 128 Jinling Road, Zhanggong District, Ganzhou City, 341000, Jiangxi Province, China.
Introduction And Hypothesis: The relationship between cesarean section scars and active pelvic floor muscle tone lacks sufficient evidence. This study is aimed at investigating the relationship between the severity of cesarean section scars and active pelvic floor muscle tone in postpartum women.
Methods: We conducted a prospective cross-sectional study of 604 women at 6-8 weeks postpartum.
Clin Kidney J
January 2025
Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
The mineralocorticoid receptor (MR) is a nuclear transcription factor that plays a critical role in regulating fluid, electrolytes, blood pressure, and hemodynamic stability. In conditions such as chronic kidney disease (CKD) and heart failure (HF), MR overactivation leads to increased salt and water retention, inflammatory and fibrotic gene expression, and organ injury. The MR is essential for transcriptional regulation and is implicated in metabolic, proinflammatory, and pro-fibrotic pathways.
View Article and Find Full Text PDFZhonghua Wei Zhong Bing Ji Jiu Yi Xue
December 2024
The Fifth Clinical Medical College, Henan University of Traditional Chinese Medicine, Zhengzhou 450003, Henan, China.
Objective: To investigate the effect of hyperbaric oxygen (HBO) on paroxysmal sympathetic hyperexcitation (PSH) after brain injury.
Methods: A multicenter retrospective study was conducted. Fifty-six patients with PSH who received HBO treatment from four hospitals in Henan Province from January 2021 to September 2023 were selected as the HBO group, and 36 patients with PSH who did not receive HBO treatment from Zhengzhou People's Hospital from May 2018 to December 2020 were selected as the control group.
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