SAbPred: a structure-based antibody prediction server.

Nucleic Acids Res

Department of Statistics, Oxford Protein Informatics Group, University of Oxford, 24-29 St Giles', Oxford, OX1 3LB, UK

Published: July 2016

SAbPred is a server that makes predictions of the properties of antibodies focusing on their structures. Antibody informatics tools can help improve our understanding of immune responses to disease and aid in the design and engineering of therapeutic molecules. SAbPred is a single platform containing multiple applications which can: number and align sequences; automatically generate antibody variable fragment homology models; annotate such models with estimated accuracy alongside sequence and structural properties including potential developability issues; predict paratope residues; and predict epitope patches on protein antigens. The server is available at http://opig.stats.ox.ac.uk/webapps/sabpred.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987913PMC
http://dx.doi.org/10.1093/nar/gkw361DOI Listing

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SAbPred: a structure-based antibody prediction server.

Nucleic Acids Res

July 2016

Department of Statistics, Oxford Protein Informatics Group, University of Oxford, 24-29 St Giles', Oxford, OX1 3LB, UK

SAbPred is a server that makes predictions of the properties of antibodies focusing on their structures. Antibody informatics tools can help improve our understanding of immune responses to disease and aid in the design and engineering of therapeutic molecules. SAbPred is a single platform containing multiple applications which can: number and align sequences; automatically generate antibody variable fragment homology models; annotate such models with estimated accuracy alongside sequence and structural properties including potential developability issues; predict paratope residues; and predict epitope patches on protein antigens.

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