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Novel imaging tools for investigating the role of immune signalling in the brain. | LitMetric

AI Article Synopsis

  • Neuro-immune interactions are crucial for understanding both healthy and diseased states of the brain and spinal cord, emphasizing the need for improved molecular analysis techniques.
  • Current imaging methods in this field, adapted from immunology and neuroscience, have limitations that hinder our understanding of the central nervous system (CNS).
  • The review focuses on presenting new and innovative imaging technologies that can better address these limitations, making it easier for medical scientists to study neuroimmune responses.

Article Abstract

The importance of neuro-immune interactions in both physiological and pathophysiological states cannot be overstated. As our appreciation for the neuroimmune nature of the brain and spinal cord grows, so does our need to extend the spatial and temporal resolution of our molecular analysis techniques. Current imaging technologies applied to investigate the actions of the neuroimmune system in both health and disease states have been adapted from the fields of immunology and neuroscience. While these classical techniques have provided immense insight into the function of the CNS, they are however, inherently limited. Thus, the development of innovative methods which overcome these limitations are crucial for imaging and quantifying acute and chronic neuroimmune responses. Therefore, this review aims to convey emerging novel and complementary imaging technologies in a form accessible to medical scientists engaging in neuroimmune research.

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Source
http://dx.doi.org/10.1016/j.bbi.2016.04.014DOI Listing

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