Ready-to-use solutions are the most preferable and most common dosage forms for injectable and topical ophthalmic products. Drugs formulated as solution almost always have chemical and physical stability challenges as well as solubility limitations and the need to prevent inadvertent microbial contamination issues. This article, which takes us through a discussion of optimizing the physical stability of solutions, represents the first of a series of articles discussing how these challenges and issues are addressed.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Advances in nanomaterials for radiation protection in the aerospace industry: a systematic review.
Nanotechnology
December 2024
CCTS/DFQM, UFSCar - Campus Sorocaba, Rod. João Leme dos Santos km 110 - SP-264 Bairro do Itinga - Sorocaba CEP 18052-780, Sorocaba, 18052-780, BRAZIL.
Nanomaterials stand out for their exceptional properties and innovative potential, especially in applications that protect against space radiation. They offer an innovative approach to this challenge, demonstrating notable properties of radiation absorption and scattering, as well as flexibility and lightness for the development of protective clothing and equipment. This review details the use of polymeric materials, such as polyimides (PIs), which are efficient at attenuating ultraviolet (UV) radiation and atomic oxygen (AO).
View Article and Find Full Text PDFDigital Applications for Videoterminal-Associated Dry Eye Disease.
Vision (Basel)
November 2024
Eye Clinic, Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.
Dry eye disease (DED) has become increasingly prevalent in the digital era, largely due to prolonged screen exposure. The excessive use of digital devices contributes to inappropriate blink frequency and dynamics, leading to ocular surface dryness and discomfort. Additionally, digital screen use has broader implications for systemic health, including visual strain, headaches, and disrupted circadian rhythms caused by blue light exposure.
View Article and Find Full Text PDFComposite Anion Exchange Membranes Containing a Long-Side Chain Ionomer and Exfoliated Lamellar Double Hydroxides.
Membranes (Basel)
December 2024
LIME Laboratory, CNRS, MADIREL (UMR 7246), Campus St Jérôme, Aix Marseille University, 13013 Marseille, France.
Anion Exchange Membranes (AEMs) are promising materials for electrochemical devices, such as fuel cells and electrolyzers. However, the main drawback of AEMs is their low durability in alkaline operating conditions. A possible solution is the use of composite ionomers containing inorganic fillers stable in a basic environment.
View Article and Find Full Text PDFPolysulfone-Based Membranes Modified with Ionic Liquids and Silica for Potential Fuel Cell Applications.
Membranes (Basel)
December 2024
Unit of Chemical Technologies, Technology Centre of Catalonia, Eurecat, 43007 Tarragona, Spain.
The urgent need for sustainable, low-emission energy solutions has positioned proton exchange membrane fuel cells (PEMFCs) as a promising technology in clean energy conversion. Polysulfone (PSF) membranes with incorporated ionic liquid (IL) and hydrophobic polydimethylsiloxane-functionalized silica (SiO-PDMS) were developed and characterized for their potential application in PEMFCs. Using a phase inversion method, membranes with various combinations of PSFs, SiO-PDMS, and 1-butyl-3-methylimidazolium triflate (BMI.
View Article and Find Full Text PDFSystem Dynamics Modeling of Scale Formation in Membrane Distillation Systems for Seawater and RO Brine Treatment.
Membranes (Basel)
November 2024
Civil and Environmental Engineering, Kookmin University, 77 Jeongneung-ro, Seongbuk-gu, Seoul 136-702, Republic of Korea.
To overcome the limitations of traditional Reverse Osmosis (RO) desalination, Membrane Distillation (MD) has gained attention as an effective solution for improving the treatment of seawater and RO brine. Despite its potential, the formation of inorganic scales, particularly calcium sulfate (CaSO), continues to pose a major challenge. This research aims to explore the scaling mechanisms in MD systems through a combination of experimental analysis and dynamic modeling.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!