Acupuncture can be used to treat various nervous system diseases. Here, 168 vascular dementia patients were orally administered donepezil hydrochloride alone (5 mg/day, once a day for 56 days), or combined with acupuncture at Shenting (DU24), Tianzhu (BL10), Sishencong (Extra), Yintang (Extra), Renzhong (DU26), Neiguan (PC6), Shenmen (HT7), Fengchi (GB20), Wangu (GB12) and Baihui (DU20) (once a day for 56 days). Compared with donepezil hydrochloride alone, P300 event related potential latency was shorter with an increased amplitude in patients treated with donepezil hydrochloride and acupuncture. Mini-Mental State Examination score was also higher. Moreover, these differences in P300 latency were identified within different infarcted regions in patients treated with donepezil hydrochloride and acupuncture. These findings indicate that acupuncture combined with donepezil hydrochloride noticeably improves cognitive function in patients with vascular dementia, and exerts neuroprotective effects against vascular dementia.
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http://dx.doi.org/10.4103/1673-5374.179059 | DOI Listing |
Alzheimers Dement
December 2024
Baehwa University, Seoul, Seoul, Korea, Republic of (South).
Background: It is difficult to predict of long-term treatment response of AD to medical treatment when starting medication. We explored EEG brain connectivity as a potential biomarker for long-term medication outcomes in patients with AD.
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Alzheimers Dement
December 2024
Pontifical Catholic University, Londrina, Parana, Brazil.
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