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Perineural Spread of Head and Neck Cancer: Ophthalmic Considerations. | LitMetric

Perineural Spread of Head and Neck Cancer: Ophthalmic Considerations.

J Neurol Surg B Skull Base

Department of Ophthalmology, University of Virginia, Charlottesville, Virginia, United States.

Published: April 2016

AI Article Synopsis

  • Head and neck cancers that affect the orbit create complex treatment choices for doctors due to the unique patterns of spread, especially through nerve pathways.
  • Misdiagnosis is common, leading to treatment delays that can worsen patient outcomes.
  • The article focuses on evaluating ocular involvement and addressing complications related to perineural spread of malignancy in the orbit.

Article Abstract

Head and neck malignancies with orbital involvement present difficult decisions to the treating physician. When the spread is perineural, the challenges are greater due to the incipient nature of the spread and the fact that the orbit can also be involved by centrifugal spread from the non-ophthalmic branches of the trigeminal nerve. The disease is often misdiagnosed and the subsequent delay in treatment results in worse outcomes. This article discusses the evaluation of the eye and the many facets of orbital involvement by perineural spread of malignancy including the treatment of complications.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846412PMC
http://dx.doi.org/10.1055/s-0036-1582239DOI Listing

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