Unlabelled: Radionuclide myocardial perfusion imaging (MPI) with single photon emission computed tomography (SPECT) has been widely used clinically as one of the major functional imaging modalities for patients with coronary artery disease (CAD) for decades. Ample evidence has supported the use of MPI as a useful and important tool in the diagnosis, risk stratification and treatment planning for CAD. Although popular in the United States, MPI has become the most frequently used imaging modality among all nuclear medicine tests in Taiwan. However, it should be acknowledged that MPI SPECT does have its limitations. These include false-positive results due to certain artifacts, false-negative due to balanced ischemia, complexity and adverse reaction arising from current pharmacological stressors, time consuming nature of the imaging procedure, no blood flow quantitation and relatively high radiation exposure. The purpose of this article was to review the recent trends in nuclear cardiology, including the utilization of positron emission tomography (PET) for MPI, new stressor, new SPECT camera with higher resolution and higher sensitivity, dynamic SPECT protocol for blood flow quantitation, new software of phase analysis for evaluation of LV dyssynchrony, and measures utilized for reducing radiation exposure of MPI.
Key Words: Coronary artery disease • Myocardial flow reserve • Myocardial perfusion imaging • Phase analysis • PET • SPECT.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816914 | PMC |
| http://dx.doi.org/10.6515/acs20150803a | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
How to perform and evaluate a myocardial perfusion imaging by computed tomography.
Eur Heart J Imaging Methods Pract
January 2025
Perioperative Cardiology and Cardiovascular Imaging Department, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, Milan 20138, Italy.
Stress computed tomography perfusion (CTP) delivers a comprehensive evaluation of both the anatomical and functional aspects in a single examination. It stands out as the only non-invasive technique capable of quantifying coronary stenosis and assessing its functional impact, offering a consolidated diagnostic and management approach for patients with confirmed or suspected coronary artery disease (CAD). This very practical review ('How to.
View Article and Find Full Text PDFImpaired myocardial perfusion and myocardial inflammation of acute myopericarditis associated with COVID-19.
J Cardiol Cases
January 2025
Department of Cardiology, Sapporo Kojinkai Memorial Hospital, Sapporo, Japan.
Unlabelled: Myocarditis and pericarditis, or myopericarditis, is a rare, albeit life-threatening, cardiac complication of coronavirus disease 2019 (COVID-19). Although most patients recover from myocardial inflammation within weeks of the acute infection, there are concerns about acute and long-term myocardial injury. Coronary microvascular dysfunction and myocardial inflammation in the affected myocardium might be key factors in developing acute COVID-19-associated myopericarditis.
View Article and Find Full Text PDFExperimental Study on Myocardial Protective Effect of Xuebijing Injection on Extracorporeal Membrane Oxygenation Perfused Isolated Heart: Based on Autophagy and NLRP3 Inflammatory Pathway.
Transplant Proc
January 2025
Guangxi Medical University, Nanning, China. Electronic address:
Background: The purpose of this study was to investigate the myocardial protective effect of Xuebijing (XBJ) injection in isolated donor heart preservation based on autophagy and NLRP3 inflammatory pathway, and to provide clues for improving the quality of donor heart preservation in the clinic.
Methods: Fourteen Guangxi Bama miniature pigs were randomly divided into two groups to establish the isolated heart perfusion model of extracorporeal membrane oxygenation (ECMO): (1) normal saline group (NS group): 50 mL normal saline was added to the perfusion solution; and (2) Xuebijing injection group (XBJ group): 10 mL of XBJ was added to the perfusate. Both groups were continuously pumped with 5 mL/h for 8 hours.
Managing Arrhythmias in Cardiogenic Shock: Insights Into Milrinone and Dobutamine Therapy.
Cureus
December 2024
Internal Medicine, Combined Military Hospital, Quetta, PAK.
Shock is a state of inadequate perfusion that affects vital organs. Cardiogenic shock (CS) predisposes patients to various arrhythmias. The adverse effect depends on intervention and pharmacogenomics.
View Article and Find Full Text PDFProgrammed cardiomyocyte death in myocardial infarction.
Apoptosis
January 2025
National Traditional Chinese Medicine Clinical Research Base, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, People's Republic of China.
Cardiovascular disease (CVD) is a leading cause of human mortality worldwide, with patients often at high risk of heart failure (HF) in myocardial infarction (MI), a common form of CVD that results in cardiomyocyte death and myocardial necrosis due to inadequate myocardial perfusion. As terminally differentiated cells, cardiomyocytes possess a severely limited capacity for regeneration, and an excess of dead cardiomyocytes will further stress surviving cells, potentially exacerbating to more extensive heart disease. The article focuses on the relationship between programmed cell death (PCD) of cardiomyocytes, including different forms of apoptosis, necrosis, and autophagy, and MI, as well as the potential application of these mechanisms in the treatment of MI.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!