AI Article Synopsis
- A study in Taiwan investigated how body mass index (BMI) impacts outcomes after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) over a period from 2005 to 2011.
- The research involved 1,298 AMI patients categorized into four BMI groups, finding that underweight individuals had lower survival rates both at 30 days and 5 years compared to overweight and obese patients.
- Ultimately, factors like older age and lack of statin use were significant predictors of mortality, while BMI itself did not significantly influence long-term survival outcomes.
Article Abstract
Background: Although there have been some studies focusing on the relationship between body mass index (BMI), coronary artery disease (CAD) and acute coronary syndrome, the clinical effects of BMI on outcomes after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) are not well known in a Taiwanese population.
Methods: From January 2005 to December 2011, 1298 AMI patients who received PCI were enrolled from a single center in Taiwan. The patients were divided into 4 groups according to their BMI: underweight (BMI < 18.5 kg/m(2)); normal weight (18.5 ≤ BMI < 24 kg/m(2)); overweight (24 ≤ BMI < 27 kg/m(2)) and obese (BMI ≥ 27). All patients had been followed up for at least 12 months, and 30-day and 5-year all-cause and cardiovascular-cause mortality were compared among the study groups.
Results: The patients in the underweight group had a lower 30-day survival rate than the other 3 groups, and the underweight and normal weight patients had a lower 5-year survival rate than the overweight and obese patients. The multivariate regression analysis showed that Killip class ≥ 2, non-use of statin, older age, hemoglobin < 12 g/dl and chronic kidney disease, but not BMI, are independent predictors of all-cause mortality.
Conclusions: In this present study, the major factors affecting long-term survival are lack of using statin and older age, but not obese paradox.
Key Words: Acute myocardial infarction; Mortality; Obesity; Percutaneous coronary intervention; Survival.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804790 | PMC |
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