AI Article Synopsis
- The study examined the behaviors of mature rats exposed to alcohol in the womb, focusing on their activities in various stress-inducing environments.
- Findings revealed a decrease in exploration and orientation, increased anxiety and fear-based responses, and difficulties in forming conditioned reflexes, suggesting a link to impaired brain function.
- The authors propose that these behavioral issues stem from brain damage caused by alcohol's harmful effects during fetal development, specifically affecting oxygen delivery to the brain.
Article Abstract
Behavior of mature rats, who had been exposed antenatally to intrauterine alcoholic intoxication, was studied in the open field settings, unavoidable swimming and Simonov's emotional resonance situations; their conditioned reflexes of passive and active avoidance were trained, arterial blood pressure was measured, and sleeping patterns examined. It was demonstrated that animals' orientation/exploration activity was reduced, while passive behavior and fear-associated emotions became more prominent, conditioned reflexes were more difficult to form, vegetative autoregulation was disturbed, and insomniac disturbances were in evidence as a result of intrauterine alcoholic intoxication. It is suggested that the above-listed disorders are rooted in hypoxic cerebral changes, induced by pathogenic effects of alcohol on the embryonal and fetal central nervous system.
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