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http://dx.doi.org/10.4187/respcare.04795 | DOI Listing |
J Clin Med
December 2024
Department of Cardiology, Umberto I Hospital, 84014 Nocera Inferiore, Italy.
Heart and lung sharing the same anatomical space are influenced by each other. Spontaneous breathing induces dynamic changes in intrathoracic pressure, impacting cardiac function, particularly the right ventricle. In intensive care units (ICU), mechanical ventilation (MV) and therefore positive end-expiratory pressure (PEEP) are often applied, and this inevitably influences cardiac function.
View Article and Find Full Text PDFPhysiol Meas
January 2025
Department of Critical Care Medicine, Peking Union Medical College Hospital, No.1 Shuaifuyuan, Dongcheng District, Dongcheng-qu, 100730, CHINA.
Prone positioning is a therapeutic strategy for severe Acute Respiratory Distress Syndrome (ARDS). In COVID-19-associated ARDS (CARDS), the application of prone position has shown varying responses, influenced by factors such as lung recruitability and SARS-CoV-2-induced pulmonary endothelial dysfunction. This study aimed to compare the early impact of pronation on lung ventilation-perfusion matching (VQmatch) in CARDS and non-COVID-19 ARDS patients (non-CARDS).
View Article and Find Full Text PDFJ Minim Access Surg
January 2025
Department of Community Medicine, ESIC Medical College and Hospital, Chennai, Tamil Nadu, India.
Introduction: Post-operative pulmonary complications (PPCs) are a significant cause of morbidity following surgery. This study evaluated the effect of intraoperative positive end-expiratory pressure (PEEP) on PPCs in overweight patients undergoing elective laparoscopic hernia surgery.
Patients And Methods: In this randomised controlled trial, 60 patients with a body mass index between 25 and 30 kg/m² were divided equally into a standard PEEP group (5 cm H2O) and a high PEEP group (10 cm H2O).
Respir Res
January 2025
School of Engineering, University of Warwick, Coventry, CV4 7AL, UK.
Introduction And Objectives: High flow nasal cannula (HFNC) therapy is an increasingly popular mode of non-invasive respiratory support for the treatment of patients with acute hypoxemic respiratory failure (AHRF). Previous experimental studies in healthy subjects have established that HFNC generates flow-dependent positive airway pressures, but no data is available on the levels of mean airway pressure (mP) or positive end-expiratory pressure (PEEP) generated by HFNC therapy in AHRF patients. We aimed to estimate the airway pressures generated by HFNC at different flow rates in patients with AHRF, whose functional lung volume may be significantly reduced compared to healthy subjects due to alveolar consolidation and/or collapse.
View Article and Find Full Text PDFFolia Med (Plovdiv)
December 2024
Medical University of Plovdiv, Plovdiv, Bulgaria.
Positive end-expiratory pressure (PEEP) titration is crucial for improving oxygenation and preventing ventilator-induced lung injury in acute hypoxemic respiratory failure. Electrical impedance tomography (EIT) offers real-time, bedside monitoring of lung ventilation distribution, potentially guiding individualized PEEP settings.
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