Polypharmacy is accentuated in our fast-growing population. Polypharmacy is associated with adverse drug reactions, interactions, non-compliance, and increased risk of geriatric syndroms (falls, incontinence, malnutrition, cognitive impairment, delirium). There is a dilemma between clinical practice guidelines and pragmatism in the treatment of elderly patients in the last ten years of life. Reducing polypharmacy is a challenge and we present some instruments for reducing polypharmacy.
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