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Investigating the availability, affordability, and market dynamics of innovative oncology drugs in Morocco: an original report.
Int J Equity Health
October 2024
Medical Oncology Department, VI University Hospital, Marrakech, Mohammed, 40000, Morocco.
Background: The cost of cancer drugs presents a significant challenge to accessibility of treatment worldwide. Projections indicate that by 2040, two-thirds of cancer cases will occur in low- and middle- income countries. Paradoxically, despite this impending burden, LMICs command less than 5% share of global resources for treating cancer.
View Article and Find Full Text PDFPulmonary embolism with thrombus in transit across a patent foramen ovale.
Oxf Med Case Reports
August 2024
Yale University School of Medicine Department of Cardiology, New Haven, CT 06510, United States.
Article Synopsis
- - The text discusses a rare and dangerous condition called impending paradoxical embolism (IPDE), exemplified by a case involving a 51-year-old man with sleep apnea who had deep vein thrombosis and pulmonary embolism.
- - The patient was found to have a saddle pulmonary embolus affecting the right atrium and a patent foramen ovale (PFO), leading to complex surgical interventions including thrombectomy and PFO closure.
- - The case highlights the challenges in diagnosing and treating thromboembolism-in-transit, noting the lack of consensus on treatment methods, while calling for more research to develop standardized management protocols.
A Rare Case of Impending Paradoxical Embolism.
Mayo Clin Proc
September 2024
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Successful surgical treatment of impending paradoxical embolism with pulmonary embolism and myocardial infarction.
J Cardiothorac Surg
March 2024
Department of Cardiovascular Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Background: Paradoxical embolism is a rare cause of acute arterial occlusion. This phenomenon arises when embolic material travels from the venous system crosses an abnormal shunt such as patent foramen ovale, atrial septal defects, ventricular septal defects, or pulmonary arteriovenous malformations, into the arterial system. Impending paradoxical embolism refers to the presence of an entrapped thrombus in the patent foramen ovale.
View Article and Find Full Text PDFQuadri-Chamber Thrombi and Impending Paradoxical Embolism: Thrombus in Transit Through Patent Foramen Ovale.
JACC Case Rep
March 2024
HonorHealth/Thompson Peak Medical Center, Scottsdale, Arizona, USA.
Thrombus-in-transit through patent foramen ovale (PFO) is an extremely rare diagnosis that can often be associated with pulmonary embolism. Currently, data exists to guide management options; however, there is no medical consensus with regard to the optimal treatment strategy for thrombus-in-transit through PFO.
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