AI Article Synopsis
- A significant portion (18% to 30%) of infantile hemangiomas (IH) are found on the extremities, categorized into localized, segmental, and minimal growth types.
- The study aimed to link the localization of extremity hemangiomas (IHE) to their arterial blood supply patterns, examining cases from 2002 to 2015.
- Results indicated that most IHE were unilateral, predominantly located on the upper extremities, and their localization corresponded to embryonic arterial supply areas, possibly linked to temporary tissue hypoxia influencing hemangioma growth during fetal development.
Article Abstract
Background: From 18% to 30% of infantile hemangiomas (IH) are located on the extremities (IHE). They can be divided into localized, segmental, and minimal or arrested growth (IH-MAG) subtypes.
Objective: We sought to correlate localization of IHE with the anatomy of the arterial vascular supply.
Methods: All children with segmental IHE and IH-MAG presenting to our department of pediatric dermatology from 2002 to 2015 were evaluated. Hemangiomas were mapped and their patterns were analyzed.
Results: Most IHE were unilateral (105/109). Two thirds (68/109) were located on the upper, and one third (41/109) on the lower extremities. Distal locations were more frequently affected. Segmental IHE were more common (upper extremities 83.8%; lower extremities 56.1%) than IH-MAG (16.2% and 43.9%, respectively). Ulceration occurred in 5.5%. Localization of IHE was found to correspond to supply areas of embryonic arterial variants.
Limitations: This was a retrospective study. Only segmental IHE and IH-MAG were evaluated. Angiographic studies were not performed.
Conclusion: The location of IHE may be related to variant anatomy of arterial supply during embryo fetal development. We hypothesize that this contributes to temporary regional tissue hypoxia during early fetal development, which is a known stimulus for the proliferation of hemangioma stem cells.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jaad.2016.03.029 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bioconversion of municipal solid waste into bio-based products: A review on valorisation and sustainable approach for circular bioeconomy.
Sci Total Environ
December 2020
Department of Chemical Engineering, Sri Sivasubramaniya Nadar College of Engineering, Kalavakkam, Chennai 603 110, Tamil Nadu, India; Department of Environmental Engineering and Water Technology, IHE Delft Institute for Water Education, PO Box 3015, 2601, DA, Delft, the Netherlands.
Municipal solid waste management is one of the major issues throughout the world. Inappropriate management of municipal solid waste (MSW) can pose a major hazard. Anaerobic processing of MSW followed by methane and biogas generation is one of the numerous sustainable energy source options.
View Article and Find Full Text PDFRegional coronary endothelial dysfunction is related to the degree of local epicardial fat in people with HIV.
Atherosclerosis
November 2018
Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA. Electronic address:
Background And Aims: Coronary artery disease (CAD) is now an important cause of premature death in people with HIV but the causes of accelerated CAD are poorly understood. Epicardial adipose tissue (EAT) is metabolically-active and thought to contribute to CAD development. We tested the hypothesis that abnormal coronary endothelial function (CEF), an early marker and mediator of atherosclerosis, is related to the amount of local pericoronary EAT in HIV.
View Article and Find Full Text PDFLocal coronary wall eccentricity and endothelial function are closely related in patients with atherosclerotic coronary artery disease.
J Cardiovasc Magn Reson
July 2017
Department of Medicine, Division of Cardiology, Johns Hopkins University, 600 N Wolfe St., Baltimore, MD, 21287, USA.
Background: Coronary endothelial function (CEF) in patients with coronary artery disease (CAD) varies among coronary segments in a given patient. Because both coronary vessel wall eccentricity and coronary endothelial dysfunction are predictors of adverse outcomes, we hypothesized that local coronary endothelial dysfunction is associated with local coronary artery eccentricity.
Methods: We used 3 T coronary CMR to measure CEF as changes in coronary cross-sectional area (CSA) and coronary blood flow (CBF) during isometric handgrip exercise (IHE), a known endothelial-dependent stressor, in 29 patients with known CAD and 16 healthy subjects.
Anatomical patterns of infantile hemangioma (IH) of the extremities (IHE).
J Am Acad Dermatol
September 2016
Department of Pediatric Dermatology, Catholic Children's Hospital Wilhelmstift, Hamburg, Germany. Electronic address:
Article Synopsis
- A significant portion (18% to 30%) of infantile hemangiomas (IH) are found on the extremities, categorized into localized, segmental, and minimal growth types.
- The study aimed to link the localization of extremity hemangiomas (IHE) to their arterial blood supply patterns, examining cases from 2002 to 2015.
- Results indicated that most IHE were unilateral, predominantly located on the upper extremities, and their localization corresponded to embryonic arterial supply areas, possibly linked to temporary tissue hypoxia influencing hemangioma growth during fetal development.
Intramural haematoma of the esophagus: multimodality imaging findings and clinical triad.
Acta Clin Belg
October 2014
Intramural haematoma of the esophagus (IHE) is an uncommon clinical condition, which can mimic other cardiothoracic emergencies in both clinical and imaging perspectives. We presented the case of a 54-year-old female who presented to the emergency department with a clinical triad of retrosternal chest pain, odynophagia, and haematemesis for 3 days. Multi-detector computed tomography (MDCT) revealed long-segmental, well-defined, isodense mass in postero-lateral wall of esophagus with smooth arc-shaped indentation into the lumen and no obvious enhancement after IV contrast administration.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!