Objective: To compare effects of secondary cleft procedures on alar base position and nostril morphology.
Design: Retrospective review.
Setting: Multidisciplinary cleft clinic at tertiary center.
Patients, Participants: Seventy consecutive patients with unilateral clefts were grouped according to secondary procedure.
Interventions: Alveolar bone graft versus total lip takedown with anatomic muscle repair versus single-stage total lip with cleft septorhinoplasty (nose-lip) versus rhinoplasty alone.
Main Outcome Measures: Anthropometric measurements were recorded from pre- and postoperative photographs. Ratios of cleft to noncleft side were compared within and across groups pre- and postoperatively using parametric and nonparametric tests.
Results: Within the bone graft group, no differences were seen postoperatively in alar base position in long-term follow-up. The total lip group demonstrated greater symmetry at the alar base (P < .001), increased vertical lip dimension (P < .001), and decreased nostril height (P = .004) postoperatively. Within the nose-lip group, increased vertical dimension and alar base support (P < .001) were also seen postoperatively. Across groups, the single-stage nose-lip group demonstrated greatest alar base symmetry on worm's-eye view (P < .04).
Conclusions: Alar base asymmetry in patients with unilateral clefts may be related to soft tissue deficiency and was not affected by alveolar bone grafting. Total lip takedown with anatomic muscle reapproximation was associated with increased alar base symmetry and vertical lip dimension on cleft to noncleft side. Greatest symmetry at the alar base was seen following single-stage nose-lip reconstruction, which may be an effective technique for correcting the secondary cleft lip nasal deformity.
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http://dx.doi.org/10.1597/15-158 | DOI Listing |
Int J Mol Sci
January 2025
Xinjiang Production & State Key Laboratory Incubation Base for Conservation and Utilization of Bio-Resource in Tarim Basin, Alar 843300, China.
The transcription factors in the ABA Response Element Binding (AREB) protein family were differentially regulated under multiple stress conditions; however, functional analyses of AREB in Oliv. had not been conducted previously. In the present study, the comprehensive identification of the gene family and the function of in response to drought stress in were elucidated.
View Article and Find Full Text PDFBeijing Da Xue Xue Bao Yi Xue Ban
February 2025
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China.
Objective: To establish a similarity measurement model for patients with dentofacial deformity based on 3D craniofacial features and to validate the similarity results with quantifying subjective expert scoring.
Methods: In the study, 52 cases of patients with skeletal Class Ⅲ malocclusions who underwent bimaxillary surgery and preoperative orthodontic treatment at Peking University School and Hospital of Stomatology from January 2020 to December 2022, including 26 males and 26 females, were selected and divided into 2 groups by sex. One patient in each group was randomly selected as a reference sample, and the others were set as test samples.
BMC Microbiol
December 2024
State Key Laboratory Incubation Base for Conservation and Utilization of Bio-Resource in Tarim Basin, Alar, Xinjiang Uygur Autonomous Region, 843300, China.
Background: Pear black spot is caused by Alternaria tenuissima. It is one of the diseases of concern limiting pear production worldwide. Existing cultivation methods and fungicides are not sufficient to control early blight.
View Article and Find Full Text PDFJ Plast Reconstr Aesthet Surg
November 2024
The Department of Perineal Plastic Surgery and Gender Reshaping of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:
Objectives: To introduce a novel technique using the buried-guided suture method for suspending the alar crus to correct nostril exposure in East Asians and to investigate its safety and efficacy.
Methods: Patients with ptotic alar crus and nostril exposure at our clinic were enrolled between December 2011 and December 2023. Via an intranasal incision, the excess skin on the inner side of the nostrils was excised.
J Clin Exp Dent
November 2024
Department of Oral and Maxillofacial Surgery, University of Pernambuco, Recife-PE, Brazil.
Background: Facial analysis for orthognathic surgery aims to identify facial features and determine how occlusion should be corrected to achieve facial balance. Several artificial neural networks have been developed to detect facial landmarks; however, no publications have reported the application of neural networks to measure facial proportions specifically for orthognathic surgery planning. Objectives: To develop a computer program that automates facial measurements through photograph capture, as well as to present the development stages of the program and the test results evaluating its effectiveness.
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