Ru(II)-Catalyzed Direct C(sp(2))-H Activation/Selenylation of Arenes with Selenyl Chlorides.

J Org Chem

CAS Key Laboratory of Receptor Research, and Synthetic Organic & Medicinal Chemistry Laboratory (SOMCL), Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences , Shanghai 201203, China.

Published: July 2016

A new ruthenium catalytic system was developed for the construction of a C(sp(2))-Se bond with the assistance of directing groups. This protocol features mild reaction conditions, wider substrate scope, and convenient late-stage selenylation of bioactive molecules.

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Source
http://dx.doi.org/10.1021/acs.joc.6b00634DOI Listing

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