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Isoniazid-induced cerebellitis in a patient with renal dysfunction.
Lung India
September 2024
Department of Radiology, PSGIMSR, Coimbatore, Tamil Nadu, India. E-mail:
The Unusual Adverse Effects of Antituberculosis Therapy in Kidney Patients.
Int J Mycobacteriol
April 2024
Department of Nephrology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Background: Chronic kidney disease (CKD) patients are at a high risk of tuberculosis (TB), with a relative risk of developing active TB of 10%-25%. Similarly, glomerular disease increases the risk of TB due to diminished glomerular filtration rate, proteinuria, and immunosuppression use. Further, the first-line anti-TB drugs are associated with acute kidney injury (AKI) even in patients with normal kidney functions.
View Article and Find Full Text PDFA Case of Isoniazid Induced Cerebellitis in a Patient with Chronic Renal Failure.
Ann Indian Acad Neurol
June 2020
Department of Neurology, Government Medical College, Kota, Rajasthan, India.
Isoniazid-induced cerebellitis with atypical involvement of the central tegmental tracts.
Acta Neurol Belg
October 2022
Department of Advanced Biomedical Sciences, University of Naples "Federico II", Via S. Pansini 5, 80131, Naples, NA, Italy.
Isoniazid: A rare drug-induced cause for bilateral dentate nuclei hyperintensity.
Indian J Radiol Imaging
July 2020
Senior Consultant Radiologist and HOD, Consultant Radiologist, Consultant Radiologist, Department of Radiology and Imaging Sciences, Meenakshi Hospital, Tanjore, Tamil Nadu, India.
Dentate nucleus, the largest deep nucleus of the cerebellum, is affected by numerous conditions, including leukodystrophies, toxins, drugs, infections, and various metabolic and inflammatory conditions. This case report is a drug-induced cerebellitis, caused by isoniazid (INH), characterized in magnetic resonance imaging (MRI) as bilateral dentate nuclei hyperintensity. Isoniazid, an antituberculosis therapy (ATT) drug, is both neurotoxic and hepatotoxic but cerebellitis is a rare complication.
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