Conclusion: Although this study did not show higher risk of oropharyngeal malignancy in HIV patients overall, they still had much higher prevalence of NHL as well as HL than HIV negative patients. Presence of cervical lymphadenopathy is unreliable in differentiating malignant oropharyngeal tumours from benign lymphoid hyperplasia in HIV patients.
Objectives: The aim of this study was to compare the histology of oropharyngeal masses between HIV positive and negative patients.
Methods: A retrospective review of 119 patients who underwent oropharyngeal biopsies in a tertiary institution between 2007-2014 and whose HIV status was known (HIV positives =47; negatives =72).
Results: Malignancies occurred in 63.8% of HIV patients and 65% of the negative group (p = 0.87). While non-Hodgkin's lymphoma (NHL), squamous cell carcinoma (SCC), and Hodgkin's lymphoma (HL) constituted 40%, 27%, and 17% of malignancies in HIV patients, respectively; in the HIV-negative group, it was 53%, 13%, and 2% for SCC, NHL, and HL, respectively (p = 0.039, 0.017, and 0.035, respectively). Reactive lymphoid proliferation accounted for 82.4% of the benign masses in the HIV positive group. Malignant tumours were recorded more in younger patient in the HIV positive than the negative group (p = 0.001).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/00016489.2016.1170878 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Four-Point C2 Fixation for Unstable Atlas Fractures: Technical Note.
Cureus
December 2024
Neurological Surgery, Cleveland Clinic Foundation, Cleveland, USA.
Traumatic burst fractures of the atlas occur with axial loading of the cervical spine. Many of these injuries can be treated by nonsurgical management with external orthosis; however, cases with transverse ligament disruption or significant C1 lateral mass displacement require internal reduction and fixation. In patients with poor bone quality in the setting of osteoporosis or chronic illness, atlanto-axial fixation and reduction of the fracture can be a challenge, necessitating extension of fusion to the occiput, which significantly limits the range of motion.
View Article and Find Full Text PDFRegression of Clinically Diagnosed Ocular Kaposi Sarcoma Post-Initiation of Highly Active Antiretroviral Therapy.
Am J Trop Med Hyg
December 2024
Department of Ophthalmology, Faculty of Medical Sciences, The University of the West Indies, St. Michael, Barbados.
Kaposi sarcoma is a low-grade vascular neoplasm linked to the human herpesvirus 8, with the AIDS-associated epidemic variant being the most common and aggressive. Although Kaposi sarcoma more commonly affects the cutaneous tissues, lymph nodes, and visceral organs, it can also be present in ocular and ocular adnexal tissues. We report a case of a 58-year-old Indo-Caribbean woman living with AIDS who presented with a large upper eyelid mass that was clinically diagnosed as Kaposi sarcoma.
View Article and Find Full Text PDFA Rare Case of Granular Cell Tumor of the Anus.
Clin Case Rep
December 2024
Division of Surgical Oncology, Department of Surgery Eastern Carolina Brody School of Medicine Greenville North Carolina USA.
Granular cell tumors (GCTs) are uncommon soft tissue neoplasms derived from Schwann cells that can arise from various regions of the body. The majority originate from the head and neck. They are rarely encountered in the gastrointestinal tract and even more rarely in the anorectal region.
View Article and Find Full Text PDFCardiac Tamponade Due to Diffuse Large B-cell Lymphoma/Plasmablastic Lymphoma in an Immunocompetent Patient.
Cureus
November 2024
Internal Medicine, St Mary Medical Center, Langhorne, USA.
Article Synopsis
- * It typically occurs in males and is characterized by extra-nodal masses, often found in the oral cavity or gastrointestinal tract, but a unique case involved a 93-year-old female without HIV showing pericardial effusion instead.
- * Diagnosis of PBL can be challenging due to atypical presentations; thus, awareness, thorough immunohistochemistry, and clinical correlation are critical for accurate identification.
Lung Nodules and Masses in Non-HIV Immunocompromised Patients: A Clinical Imaging Algorithmic Approach.
Chest
November 2024
Department of Infectious Diseases, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Topic Importance: The incidence of pulmonary nodules and masses in non-HIV immunocompromised patients has significantly increased due to advancements in hematopoietic stem cell transplantation (HSCT) and solid organ transplantation (SOT) and the widespread use of chemotherapy and immunosuppressive therapies. Differentiating between infectious and noninfectious causes is critical for appropriate diagnosis and management, especially because radiologic and clinical presentations can be nonspecific.
Review Findings: This review provides a practical framework for evaluating pulmonary nodules and masses in non-HIV immunocompromised patients, incorporating clinical, immunologic, and radiologic features.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!