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Unravelling a mystery of hypokalemic hypertension- a rare case report of a reninoma.
BMC Endocr Disord
December 2024
National Hospital of Sri Lanka, Colombo, Sri Lanka.
Background: Reninoma is a rare cause of secondary hypertension, which can be cured with surgery if identified early before any target organ damage occurs. It leads to hypokalaemia and hypertension and typically responds well to treatment with renin-angiotensin-aldosterone system blockers. However, confirmation of the diagnosis and the localisation of this rare culprit lesion can be challenging.
View Article and Find Full Text PDFReninoma: an unusual cause of growth failure.
J Pediatr Endocrinol Metab
January 2025
Department of Endocrinology and Diabetes, Max Super Speciality Hospital, Saket, Delhi, India.
Objectives: Growth failure can result from various underlying causes, necessitating a thorough evaluation. Reninoma, a rare renin-secreting tumor, is an uncommon cause of hypertension, especially in paediatric patients, and has not been associated with growth failure until now.
Case Presentation: An 11-year-old girl presented with complaints of poor height gain, headaches, increased thirst, and vomiting.
A locally infiltrative juxtaglomerular cell tumor with unusual histologic features.
Virchows Arch
October 2024
Department of Anatomic Pathology, 12 of October University Hospital, Madrid, Spain.
Juxtaglomerular cell tumor (JGCT) is an exceptionally rare renal tumor with a predominantly benign clinical course and classically bland histology. It commonly presents in young adults and manifests as hypertension related to renin secretion. We report a JGCT initially thought to be a renal cell carcinoma.
View Article and Find Full Text PDFDiagnostic challenges in patients with reninomas and extrarenal renin-producing tumours.
Clin Endocrinol (Oxf)
July 2024
Department of Endocrinology, Skåne University Hospital, Lund, Sweden.
Renin-secreting tumours are rare causes of secondary hypertension and hypokalaemia. They are usually surgically curable, hence proper diagnostic work-up and tumour localisation is essential. In this paper, we present three Swedish patients recently diagnosed with renin secreting tumours, two with reninomas and one with an extrarenal renin-producing tumour, to illustrate diagnostic challenges.
View Article and Find Full Text PDFJuxtaglomerular Cell Tumor Mimicking Renal Cell Carcinoma on 99m Tc-MIBI SPECT/CT.
Clin Nucl Med
July 2024
From the Department of Neurology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine.
Juxtaglomerular cell tumor or reninoma is an extremely rare, typically benign, renin-secreting tumor of the kidney that causes secondary hypertension. We describe 99m Tc-MIBI SPECT/CT findings in a case of juxtaglomerular cell tumor. The renal tumor showed isodensity and photopenia on 99m Tc-MIBI SPECT/CT.
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