AI Article Synopsis

  • Routine surveillance in Guangxi Province, China, showed an increase in P[4] rotaviruses in children with acute diarrhea in 2014.
  • Despite attempting VP7 genotyping, researchers couldn't determine the specific strains of these rotaviruses.
  • However, analyses indicated that the G genotype was G2, which belongs to a new evolutionary lineage distinct from previously known lineages, raising concerns about its potential global spread.

Article Abstract

Routine surveillance revealed that the prevalence of P[4] rotaviruses circulating in children with acute diarrhea in Guangxi Province, China, increased in 2014. However, VP7 genotyping for these P[4] rotaviruses was unsuccessful. Exhaustive database searching and sequence analysis indicated that the G genotype of these P[4] rotaviruses was G2, and the VP7 genes clustered with recently emerging G2 strains in several countries within an emergent evolutionary lineage that was distinct from the previously designated lineages I-IV as well as lineage V including porcine rotaviruses. Further studies are essential to monitor the potential global spread of this emerging G2 rotavirus.

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http://dx.doi.org/10.1007/s00705-016-2852-5DOI Listing

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