Epstein-Barr virus-associated iris smooth muscle tumor with epithelioid morphology in AIDS patients: a case report.

Int Med Case Rep J

Department of Pathology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.

Published: April 2016

Importance: Report of an acquired immunodeficiency syndrome (AIDS) patient with Epstein-Barr virus (EBV)-associated iris smooth muscle tumor.

Observations: A 14-year-old African American female diagnosed with AIDS developed a painless iris mass in the right eye for 10 months. Iridocyclectomy was performed, and the pathology indicated EBV-associated iris smooth muscle tumor with epithelioid morphology. Immunohistochemical stains and in situ hybridization for EBV-encoded ribonucleic acid are very useful diagnostic tools for definite diagnosis. At 14-month follow-up, the patient did not have any tumor recurrence.

Conclusion: This is the case report of EBV-associated iris smooth muscle tumor in a person diagnosed with AIDS with a unique epithelioid morphologic feature.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822807PMC
http://dx.doi.org/10.2147/IMCRJ.S96837DOI Listing

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