Sixteen compounds have been isolated from the EtOAc fraction of 95% ethanolic extract of Sophora dunnii through silica gel, Sephadex LH-20 and semi-prerarative HPLC column chromatographies. Their structures were identified on the basis of NMR and MS spectra data as phaseollidin (1), L-maackiain (2), 2-(2',4'-dihidroxyphenyl)-5,6-methylenedioxy benzofuran (3), 8-demethyl-farrerol (4), liquiritigenin (5), genistein (6), 6-methylgenistein (7), 5-O-methyl genistein (8), 7,2',4'-trihydroxys-5-methoxy-isoflavanone (9), 7, 3', 4'-trihydroxy-isoflavanone (10), erythribyssin D (11), calycosin (12), trans-resveratrol (13), cis-resveratrol (14), stigmasterol (15), β-sitosterol (16). Among these, compounds 1-14 and 16 were isolated from this plant for the first time.
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Curr Med Mycol
May 2024
Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Background And Purpose: species are well-known antifungal medicinal plants. (Apiaceae family) is a rarely investigated plant endemic to Iran. The present study aimed to assess the antifungal, antibacterial, antioxidant, and cytotoxic activities of root extracts of different plants.
View Article and Find Full Text PDFNat Prod Res
December 2024
Programa de Pós-Graduação em Química, Universidade Federal do Ceará, Fortaleza, Brazil.
A new sesquiterpene, 8,11-epoxy-cadi-3,9-diene (), along with nine known compounds (-), were isolated from the heartwood of . Their structures were elucidated based on NMR spectroscopic data, and by comparison with data previously reported in literature. The hexane extract from the heartwood of , the EtOH extract from the heartwood of , the CHCl-soluble fraction of the EtOH extract, the EtOAc-soluble fraction of the EtOH extract and the compounds - have been evaluated as acetylcholinesterase inhibitors, and among these, the extracts and fractions exhibited satisfactory results.
View Article and Find Full Text PDFNat Prod Res
December 2024
Laboratório de Fitoquímica, Química Medicinal e Metabolômica - LFQMM - Instituto de Química - Universidade Federal de Alfenas - UNIFAL, Alfenas, MG, Brazil.
The fall armyworm is the most prevalent plague in crops associated with a reduction in corn production by up to 34%. Pesticides have been used to reduce this plague, but they cause several environmental problems including resistance, ecological imbalance, and toxicity to the final consumer. The use of plant extracts has been an effective manner of eradicating this plague from crop plantations.
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November 2024
Graduate School of Engineering, Muroran Institute of Technology, Muroran 050-8585, Japan.
Alzheimer's disease (AD) is a highly prevalent neurodegenerative disease hallmarked by amyloid plaques and neurofibrillary tangles. Amyloid plaques are formed by the amyloid β (Aβ) aggregation, so substances that inhibit this aggregation are useful for preventing and treating AD. Mushrooms are widely used medicinal fungi with high edible and nutritional value.
View Article and Find Full Text PDFPhytomedicine
December 2024
School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China; Hubei Shizhen Laboratory, Hubei University of Chinese Medicine, Wuhan, 430065, China. Electronic address:
Background: Artemisia argyi is a well-known medicinal plant. A. argyi has been widely used in clinical for about 3000 years, owing to its extensive pharmacological activity.
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